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Table 3 Cox regression for 90 day mortality AKI stage and adjusted for age, gender, co-morbidity (Diabetes Mellitus; hypertension; heart failure; vascular disease; malignancy; composite of infection; composite of GI blood loss or hypovolemia) and CRP

From: Hospital acquired Acute Kidney Injury is associated with increased mortality but not increased readmission rates in a UK acute hospital

  Hazard Ratio 95% Confidence intervals P value
   Lower Upper  
AKI stage1 1.257 1.017 1.554 0.034
AKI stage2 1.555 1.119 2.160 0.009
AKI stage 3 2.390 1.612 3.544 <0.001
Male gender 0.938 0.871 1.010 0.091
Age (reference [18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35] years)
 Age 36–45 3.048 2.103 4.415 <0.001
 Age 46–55 5.162 3.687 7.228 <0.001
 Age 56–65 8.320 6.044 11.454 <0.001
 Age 66–75 12.384 9.047 16.953 <0.001
 Age > 75 24.881 18.320 33.792 <0.001
 Diabetes Mellitus 1.028 0.925 1.143 0.605
 Hypertension 0.754 0.693 0.821 <0.001
 Ischaemic Heart Disease 0.825 0.704 0.968 0.018
 Heart Failure 1.657 1.443 1.903 <0.001
 Vascular Disease 1.656 1.289 2.126 <0.001
 Malignancy 6.340 5.864 6.855 <0.001
 Composite of Infection 1.047 0.932 1.177 0.439
 Liver Disease 2.166 1.802 2.604 <0.001
 Composite of GI Blood Loss or Hypovolaemia 1.813 1.575 2.086 <0.001
CRP (referenced to CRP < 11)
 Unmeasured 1.496 1.247 1.795 <0.001
 11–20 1.504 1.218 1.856 <0.001
 21–30 1.902 1.541 2.348 <0.001
 31–40 2.108 1.700 2.614 <0.001
 41–50 1.837 1.451 2.326 <0.001
 51–60 2.557 2.052 3.187 <0.001
 61–70 2.827 2.248 3.556 <0.001
 71–80 2.411 1.904 3.054 <0.001
 81–90 1.994 1.525 2.608 <0.001
 91–100 2.585 2.193 3.047 <0.001
 101–150 2.369 1.968 2.852 <0.001
 151–200 2.421 1.998 2.935 <0.001
 201–250 2.238 1.769 2.832 <0.001
 251–300 2.359 1.817 3.064 <0.001
 301–350 1.725 1.113 2.674 0.015
 351–400 0.927 0.801 1.074 0.313
  > 400 1.836 1.231 2.740 0.003
  1. AKI acute kidney injury, CRP C-reactive protein