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Table 4 Cox regression for readmission within 90 days for AKI or no AKI and adjusted for age, gender, co-morbidity (Diabetes Mellitus; hypertension; heart failure; vascular disease; malignancy; composite of infection; composite of GI blood loss or hypovolemia) and CRP

From: Hospital acquired Acute Kidney Injury is associated with increased mortality but not increased readmission rates in a UK acute hospital

 

Hazard Ratio

95% Confidence intervals

P value

  

Lower

Upper

 

AKI

0.921

0.787

1.078

0.304

Male gender

0.932

0.891

0.974

0.002

Age (reference [18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35] years)

 Age 36–45

1.076

0.983

1.178

0.113

 Age 46–55

1.254

1.151

1.366

<0.001

 Age 56–65

1.261

1.159

1.374

<0.001

 Age 66–75

1.441

1.325

1.567

<0.001

 Age > 75

1.784

1.656

1.921

<0.001

 Diabetes Mellitus

1.186

1.108

1.269

<0.001

 Hypertension

0.939

0.888

0.994

0.029

 Ischaemic Heart Disease

1.107

1.011

1.212

0.028

 Heart Failure

1.372

1.234

1.527

0.000

 Vascular Disease

1.194

0.983

1.450

0.073

 Malignancy

2.112

1.975

2.258

<0.001

 Composite of Infection

1.149

1.057

1.249

0.001

 Liver Disease

1.776

1.556

2.027

<0.001

 Composite of GI Blood Loss or Hypovolaemia

1.259

1.116

1.420

<0.001

CRP (referenced to CRP < 11)

 Unmeasured

1.010

0.915

1.115

0.848

 11–20

1.069

0.950

1.204

0.267

 21–30

1.051

0.920

1.200

0.463

 31–40

1.107

0.960

1.276

0.163

 41–50

1.139

0.983

1.320

0.084

 51–60

1.092

0.931

1.282

0.279

 61–70

1.137

0.962

1.344

0.132

 71–80

1.069

0.899

1.272

0.450

 81–90

.930

0.762

1.134

0.471

 91–100

1.068

0.957

1.191

0.238

 101–150

1.087

0.957

1.235

0.199

 151–200

1.096

0.957

1.255

0.186

 201–250

1.088

0.918

1.290

0.332

 251–300

0.763

0.611

0.954

0.018

 301–350

1.327

1.020

1.726

0.035

 351–400

0.843

0.788

0.902

<0.001

  > 400

1.042

0.788

1.378

0.773

  1. AKI acute kidney injury, CRP C-reactive protein