Table 1 Patient characteristics
Parameters | Missing | Total (n = 56) | No-Overcorrection (n = 45) | Overcorrection (n = 11) | p-value |
|---|---|---|---|---|---|
Age, years old | 0 | 78 (60–83) | 79 (63–84) | 60 (48–82) | 0.129 |
Male | 0 | 27 (48.2) | 22 (48.9) | 5 (45.5) | 0.838 |
Body weight, kg | 0 | 52 (42–60) | 50 (40–58) | 56 (51–69) | 0.049 |
Symptoms | |||||
Severe symptoms | |||||
Seizures | 0 | 3 (5.4) | 0 (0.0) | 3 (27.3) | <0.001 |
Coma | 0 | 0 (0.0) | 0 (0.0) | 0 (0.0) | – |
Cardiorespiratory distress | 0 | 0 (0.0) | 0 (0.0) | 0 (0.0) | – |
Other symptoms | |||||
Vomit | 0 | 13 (23.2) | 9 (20.0) | 4 (36.4) | 0.249 |
Nausea | 0 | 9 (16.1) | 7 (15.6) | 2 (18.2) | 0.832 |
Loss of appetite | 0 | 10 (17.9) | 10 (22.2) | 0 (0.0) | 0.085 |
Disorientation | 0 | 34 (60.7) | 28 (62.2) | 6 (54.5) | 0.640 |
Impairment of gait or fall | 0 | 10 (17.9) | 9 (20.0) | 1 (9.1) | 0.397 |
General fatigue | 0 | 3 (5.4) | 3 (6.7) | 0 (0.0) | 0.379 |
Asymptomatic | 0 | 3 (5.4) | 2 (4.4) | 1 (9.1) | 0.540 |
Cause of hyponatremia | |||||
Primary polydipsia | 0 | 6 (10.7) | 2 (4.4) | 4 (36.4) | 0.002 |
Poor solute intake | 0 | 21 (37.5) | 17 (37.8) | 4 (36.4) | 0.931 |
Hypovolemic hyponatremia | 0 | 36 (64.3) | 30 (66.7) | 6 (54.5) | 0.452 |
SIADH | 0 | 4 (7.1) | 4 (8.9) | 0 (0.0) | 0.305 |
Physiological stimulation of ADH | 0 | 11 (19.6) | 9 (20.0) | 2 (18.2) | 0.892 |
CSW | 0 | 2 (3.6) | 2 (4.4) | 0 (0.0) | 0.476 |
Drug intoxication | 0 | 10 (17.9) | 8 (17.8) | 2 (18.2) | 0.975 |
Unidentified | 0 | 1 (1.8) | 1 (2.2) | 0 (0.0) | 0.618 |
Underlying disease | |||||
Psychiatric disease | 0 | 6 (10.7) | 3 (6.7) | 3 (27.3) | 0.048 |
Schizophrenia | 0 | 1 (1.8) | 0 (0.0) | 1 (9.1) | 0.041 |
Anorexia nervosa | 0 | 1 (1.8) | 1 (2.2) | 0 (0.0) | 0.618 |
Depression | 0 | 3 (5.4) | 2 (4.4) | 1 (9.1) | 0.540 |
Development disorder | 0 | 1 (1.8) | 0 (0.0) | 1 (9.1) | 0.041 |
Infectious disease | 0 | 14 (25.0) | 13 (28.9) | 1 (9.1) | 0.174 |
Urinary tract infection | 0 | 5 (8.9) | 4 (8.9) | 1(9.1) | 0.983 |
Pneumonia | 0 | 3 (5.4) | 3 (6.7) | 0 (0.0) | 0.379 |
Thoracic empyema | 0 | 1 (1.8) | 1 (2.2) | 0 (0.0) | 0.618 |
Meningitis | 0 | 2 (3.6) | 2 (4.4) | 0 (0.0) | 0.476 |
Influenza | 0 | 2 (3.6) | 2 (4.4) | 0 (0.0) | 0.476 |
Cellulitis | 0 | 2 (3.6) | 2 (4.4) | 0 (0.0) | 0.476 |
HIV | 0 | 1 (1.8) | 1 (2.2) | 0 (0.0) | 0.618 |
Malignant disease | 0 | 6 (10.7) | 5 (11.1) | 1 (9.1) | 0.846 |
Stomach | 0 | 1 (1.8) | 1 (2.2) | 0 (0.0) | 0.618 |
Pancreatic | 0 | 2 (3.6) | 2 (4.4) | 0 (0.0) | 0.476 |
Renal | 0 | 1 (1.8) | 1 (2.2) | 0 (0.0) | 0.618 |
Prostatic | 2 (3.6) | 1 (2.2) | 1 (9.1) | 0.271 | |
Alcohol abuse | 0 | 4 (7.1) | 3 (6.7) | 1 (9.1) | 0.780 |
Unidentified | 0 | 28 (50.0) | 23 (51.1) | 5 (45.5) | 0.737 |
Medication on admission | |||||
Thiazide | 0 | 7 (12.5) | 5 (11.1) | 2 (18.2) | 0.525 |
Antipsychotic drug | 0 | 2 (3.6) | 2 (4.4) | 0 (0.0) | 0.476 |
DDAVP | 0 | 2 (3.6) | 2 (4.4) | 0 (0.0) | 0.476 |