Skip to main content
Fig. 3 | BMC Nephrology

Fig. 3

From: Injury induced expression of caveolar proteins in human kidney tubules - role of megakaryoblastic leukemia 1

Fig. 3

Suppression of caveolins and cavins by H2O2 in primary kidney epithelial cells. To explore putative causative mechanisms for the induction of caveolar mRNA and proteins in sclerotic kidneys, primary renal epithelial cells were cultured in vitro with and without H2O2 exposure. The mRNA levels were analyzed by qPCR at 24 h (a) and by Western blotting at 24-72 h (b-d). c and d show the quantification of Western blot results for PTRF/CAVIN1 and SDPR/CAVIN2, *(p < 0.05), n = 6. Induction of oxidative stress was confirmed by increased oxidation of Prx-SO3

Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us