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Table 2 Renal Indices at time of Biopsy

From: The increasing rates of acute interstitial nephritis in Australia: a single centre case series

Renal Indice

Urine White Cells (per HPF)

(%)

  < 10

11 (27.5)

 10–100

24 (60.0)

 100<

5 (12.5)

Urinary Eosinophils

(%)

 Present

3 (7.5)

 Absent

4 (10)

 Not tested

33 (82.5)

Urine Protein Creatinine Ratio

(%)

 Less than15 mg/mmol Cr

5 (12.5)

 More than15 mg/mmol Cr

22 (55)

 Not tested

13 (32.5)

Co-existent Disease on Biopsy

 Hypertensive Nephrosclerosis

6 (15)

 Diabetic Nephropathy

4 (10)

Serum Creatinine (μmol/L)

(IQR)

 All patients

246 (164–350)

Gender

 Male

261 (207–419)

 Female

228 (138–333)

 P

0.24

Presumed Cause of AIN

 Unknown (n = 14)

240 (164–439)

 Antibiotic (n = 7)

430 (274–454)

 Non-Steroidal Anti-Inflammatory Drugs

219 (117-248)

 (NSAIDS) (n=5)

 

 PPI/H2 antagonist (n=4)

289 (245-332)

 Immune mediated diseases (n=7)

178 (125-217)

 Other (n=3)

388 (248-473)

 P

0.16

Treatment

 

 Steroid therapy

237 (164-332)

 No treatment given

260 (164-430)

 P

0.59

Co-existent Disease on Biopsy

 

 Hypertensive Nephrosclerosis

330 (171-436)

 Diabetic Nephropathy

244 (168-245)

 No co-existent disease

242 (162-347)

 P

0.55

AKIN Severity (n=12)*

 

 1 (7)

164 (140-210)

 2 (3)

197 (155-268)

 3 (6)

380 (286-442)

 P

0.01

  1. *Only 12 patients had serum creatinine measured 3-12 months prior to renal biopsy