Table 1 Describe baseline characteristics of subjects

Sample Size

15,032

10,560

623

3849

17,074

14,587

588

1899

Age

61.0 (11.0)

61.0 (11.2)

63.2 (10.9)

60.6 (10.6)

<0.001

65.7 (13.9)

65.5 (14.3)

68.2 (11.4)

66.4 (10.8)

<0.001

Male

4048 (27)

2671 (25)

220 (35)

1157 (30)

<0.001

7659 (45)

6541 (45)

269 (46)

849 (45)

0.901

BMI

23.7 (4.0)

23.4 (4.0)

23.4 (3.9)

24.5 (4.0)

<0.001

21.8 (4.3)

21.5 (4.3)

22.5 (4.1)

23.2 (4.4)

<0.001

SBP

128.0 (20.2)

124.0 (19.8)

127.7 (20.6)

131.1 (19.7)

<0.001

127.8 (23.9)

124.4 (23.1)

135.1 (23.8)

137.3 (23.5)

<0.001

DBP

77.4 (11.4)

75.7 (11.3)

77.3 (11.3)

78.8 (11.4)

<0.001

77.4 (17.4)

75.9 (18.5)

80.3 (13.6)

81.6 (13.4)

<0.001

 Hypertension

7059 (47)

3632 (34)

480 (77)

2947 (77)

<0.001

6742 (39)

4466 (31)

510 (87)

1766 (93)

<0.001

 CVD

1712 (11)

1129 (11)

98 (16)

485 (13)

<0.001

2659 (16)

2108 (14)

122 (21)

429 (23)

<0.001

 HDL

37.7 (11.0)

37.4 (10.8)

37.3 (10.5)

38.5 (11.5)

<0.001

40.2 (9.0)

40.0 (8.6)

40.8 (10.7)

41.6 (11.2)

<0.001

 LDL

115.3 (40.5)

114.6 (39.9)

114.8 (40.0)

117.3 (42.1)

0.002

115.2 (32.8)

114.2 (31.2)

119.7 (39.3)

121.0 (41.2)

<0.001

 A1

8657 (58)

5975 (57)

383 (61)

2299 (60)

<0.001

11,079 (65)

9133 (63)

432 (73)

1514 (80)

<0.001

 A2

3367 (22)

2499 (24)

100 (16)

768 (20)

<0.001

3485 (20)

3188 (22)

77 (13)

220 (12)

<0.001

 A3

3008 (20)

2086 (20)

140 (22)

782 (20)

<0.001

2510 (15)

2266 (16)

79 (13)

165 (9)

<0.001

 GFR

48.0 (19.0)

47.1 (19.4)

42.7 (18.3)

51.2 (17.6)

<0.001

46.0 (22.5)

45.9 (23.5)

41.4 (16.5)

47.9 (14.2)

<0.001

 FU time^*

4.7(0.3–13.2)

4.9 (0.3–14.2)

2.6 (0.3–11.9)

4.5 (1.0–13.9)

<0.001

4.2(0.3,14.3)

4.3(0.2–4.3)

3.0(0.3–3.7)

4.2(1.0–13.3)

<0.001