Persistent hematuria in patients with antineutrophil cytoplasmic antibody-associated vasculitis during clinical remission: chronic glomerular lesion or low-grade active renal vasculitis?

Table 3 Predictors of end-point events as analyzed by multivariate Cox regression

Factor	HR (95% CI)	P value
Age^a	1.31(0.87,1.96)	0.19
Sex (male versus female)	1.25(0.45,3.46)	0.67
Hypertension (Yes/No)	1.40(0.50,3.91)	0.52
Cardiovascular disease (Yes/No)	1.81(0.56,5.93)	0.33
Diabetes (Yes/No)	0.38(0.07,2.00)	0.25
Using ACEI/ARB (Yes/No)	0.89(0.31,2.57)	0.83
Proteinuria (g/24 h)
< 0.5	1.00 (ref)	Ref
0.5–1.0	0.49(0.09,2.81)	0.43
> 1.0	1.56(0.51,4.73)	0.44
Baseline eGFR (mL/min/1.73m²)^b	0.73(0.59,0.91)	0.005
Persistent hematuria (Yes/No)	3.31(1.13,9.67)	0.028

Abbreviations: ACEI Angiotensin-converting enzyme inhibitors, ARB Angiotensin II receptor blocker, eGFR Estimated glomerular filtration rate
The bold represents P value < 0.05
^aFor every 10 years increase. ^bFor every increase by 10 mL/min/1.73 m²

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