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Table 1 The baseline clinical characteristics in MP group and control group

From: The impact of intravenous methylprednisolone pulses on renal survival in anti-neutrophil cytoplasmic antibody associated vasculitis with severe renal injury patients: a retrospective study

 

MP group

(n = 57)

Control group

(n = 54)

P value

Age (year)

56.9 ± 12.7

60.5 ± 12.3

0.206

Female (n, %)

41, 73.7

30, 55.6

0.079

White blood cells (109/L)

9.0 ± 4.8

7.8 ± 3.6

0.144

Hemoglobin (g/L)

73.5 ± 13.1

74.1 ± 13.8

0.824

Platelet (109/L)

211.2 ± 84.7

191.4 ± 93.4

0.244

Serum albumin (g/L)

31.1 ± 5.0

32.1 ± 5.3

0.282

Serum globulin (g/L)

30.3 ± 5.2

29.2 ± 6.2

0.282

Alanine transaminase (u/L)

14.7 ± 12.2

12.2 ± 8.1

0.205

Serum creatinine (μmol/L)

654.0 ± 202.7

715.9 ± 171.0

0.086

 ≥500 μmol/L (case, %)

50, 92.6

46, 80.7

0.095

eGFR (ml/min/1.73 m2)

7.0 ± 1.9

6.5 ± 1.8

0.147

UPCR (g/24 h)

3.1 ± 1.7

3.4 ± 2.6

0.423

 ≥3.5g/24h (case, %)

15, 27.8

18, 35.3

0.528

ESR (mm/h)

89.9 ± 38.0

75.3 ± 37.3

0.057

CRP (mg/L)

43.2 ± 49.0

37.0 ± 44.4

0.498

MPO-ANCA positive (case, %)

51, 89.5

51, 94.4

0.491

PR3-ANCA positive (case, %)

7, 12.3

3, 5.6

0.322

Pulmonary involvement (case, %)

42, 73.7

39, 72.2

1.000

BVAS

15.2 ± 3.0

15.4 ± 2.9

0.681

Kidney length (cm)

10.7 ± 1.1

9.8 ± 1.4

0.001

P/P+IVC/P+MMF/P+others (case)

7/28/21/1

14/21/16/3

0.177

  1. eGFR Estimated glomerular filtration rate, UPCR Urine protein creatinine ratio, ESR Erythrocyte sedimentation rate, CRP C reactive protein, MPO myeloperoxidase, PR3 Proteinase 3, BVAS Birmingham Vasculitis Activity Score, IVC Intravenous cyclophosphamide, MMF Mycophenolate mofetil, P Prednisone