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Table 2 CKD classification and correlation of eGFR with risk factors

From: Comparison of equations for estimating glomerular filtration rate in screening for chronic kidney disease in asymptomatic black Africans: a cross sectional study

 

CGb

4v–MDRD

4v–MDRDa

CKD-EPI

CKD-EPIa

FAS

CKD classification based on eGFR

No. (%)

 G1

478 (89.7%)

473 (88.7%)

329 (61.7%)

499 (93.6%)

433 (81.2%)

402 (75.4%)

 G2

54 (10.1%)

60 (11.3%)

199 (37.3%)

34 (6.4%)

99 (18.6%)

129 (24.2%)

 G3a

1 (0.2%)

0 (0.0%)

5 (0.9%)

0 (0.0%)

1 (0.2%)

2 (0.4%)

No. (%) below 40 years with eGFR< 75 ml/min/1.73m2 (n = 270)

0 (0.0%)

0 (0.0%)

21 (7.8%)

0 (0.0%)

1 (0.4%)

5 (1.9%)

eGFR (ml/min/1.73m2) mean (SD)

 18–29 years (n = 135)

149.0 (40.9)

129.5 (21.8)

106.8 (18.0)

135.3 (15.6)

117.2 (13.5)

108.9 (15.5)

 30–39 years (n = 135)

136.7 (39.2)

112.1 (20.2)

92.6 (16.7)

119.1 (15.8)

103.2 (13.7)

102.9 (15.8)

 40–49 years (n = 132)

139.8 (43.6)

117.0 (25.4)

96.6 (20.9)

117.6 (14.8)

101.8 (12.8)

106.7 (19.8)

 50–65 years (n = 131)

120.8 (35.1)

111.9 (25.0)

92.3 (20.6)

107.6 (15.2)

93.2 (13.1)

92.2 (18.4)

Multiple correlation coefficient (R)

0.563

0.305

0.306

0.568

0.568

0.350

Unstandardized (B) coefficients (standard error)

 Age

−0.621* (0.151)

−0.322* (0.102)

−0.267* (0.084)

−0.673* (0.067)

−0.579* (0.058)

−0.403* (0.077)

 BMI

7.418* (0.567)

−0.596 (0.382)

−0.491 (0.315)

−0.188 (0.252)

−0.129 (0.218)

−0.405 (0.289)

 Systolic BP

−0.485* (0.140)

−0.121 (0.094)

−0.099 (0.078)

−0.116 (0.062)

−0.102 (0.054)

−0.119 (0.071)

 Diastolic BP

0.237 (0.202)

0.139 (0.136)

0.115 (0.112)

0.142 (0.090)

0.124 (0.078)

0.117 (0.103)

 Abd.Circ.

−2.049* (0.231)

−0.178 (0.156)

−0.148 (0.128)

−0.184 (0.103)

−0.172 (0.089)

−0.028 (0.118)

 FPG

0.579 (1.170)

1.106 (0.788)

0.912 (0.650)

0.610 (0.519)

0.500 (0.450)

0.807 (0.596)

  1. KEY: Abd.Circ. Abdominal circumference, BP Blood pressure, BMI Body Mass Index, CKD Chronic kidney disease, FPG Fasting plasma glucose, aNot corrected for race, bCorrected for body surface area, * Significant at a p-value <0.05