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Table 2 Relation between renal damage at six months and prodromal phase length

From: Relation between duration of the prodromal phase and renal damage in ANCA-associated vasculitis

Renal damage at 6 months

   

Univariable analysis

Multivariable analysis

 

T ≤ 22 weeks

T > 22 weeks

OR (95% CI)

p-value

OR (95%CI)

p-value

eGFR ≤50 ml/min at 6 months, no (%)

21/35 (60)

19/36 (53)

0.75 (0.29–1.91)

0.54

0.89(0.33–2.37)a

0.52

Proteinuria at 6 months, no (%)

12/28 (43)

22/29 (76)

4.19 (1.14–13.01)

0.01

5.38 (1.47–19.62)b

0.002

ESRD, no (%)

3 (8)

4 (11)

1.38 (0.29–6.63)

0.69

n/a

 
  1. BVAS/WG Birmingham Vasculitis Activity Score specific for Wegener’s Granulomatosis, ESRD end-stage renal disease, GPA granulomatosis with polyangiitis, n/a not applicable, T ≤ 22 weeks prodromal phase ≤22 weeks, T > 22 weeks prodromale phase >22 weeks
  2. aadjusted for age. The variables sex, GPA versus no GPA and BVAS/WG did not meet the confounder criteria
  3. badjusted for GPA versus no GPA. The variables age, sex and BVAS/WG did not meet the confounder criteria. Multivariable logistic regression analysis for ESRD at 6 months was not performed due to a low number of events in both groups
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BMC Nephrology

ISSN: 1471-2369

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