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Table 2 Relation between renal damage at six months and prodromal phase length

From: Relation between duration of the prodromal phase and renal damage in ANCA-associated vasculitis

Renal damage at 6 months
    Univariable analysis Multivariable analysis
  T ≤ 22 weeks T > 22 weeks OR (95% CI) p-value OR (95%CI) p-value
eGFR ≤50 ml/min at 6 months, no (%) 21/35 (60) 19/36 (53) 0.75 (0.29–1.91) 0.54 0.89(0.33–2.37)a 0.52
Proteinuria at 6 months, no (%) 12/28 (43) 22/29 (76) 4.19 (1.14–13.01) 0.01 5.38 (1.47–19.62)b 0.002
ESRD, no (%) 3 (8) 4 (11) 1.38 (0.29–6.63) 0.69 n/a  
  1. BVAS/WG Birmingham Vasculitis Activity Score specific for Wegener’s Granulomatosis, ESRD end-stage renal disease, GPA granulomatosis with polyangiitis, n/a not applicable, T ≤ 22 weeks prodromal phase ≤22 weeks, T > 22 weeks prodromale phase >22 weeks
  2. aadjusted for age. The variables sex, GPA versus no GPA and BVAS/WG did not meet the confounder criteria
  3. badjusted for GPA versus no GPA. The variables age, sex and BVAS/WG did not meet the confounder criteria. Multivariable logistic regression analysis for ESRD at 6 months was not performed due to a low number of events in both groups