Skip to main content

Table 3 Bivariable cox regression analyses for the relation between prodromal phase length and 3 year ESRD/mortality as a composite outcome

From: Relation between duration of the prodromal phase and renal damage in ANCA-associated vasculitis

Relation between prodromal phase length and ESRD/mortality

Prodromal phase >22 weeks

HR (95% CI)

p-value

Univariable analysis

5.22 (1.13–24.20)

0.02

Analysis adjusted for confounders:

 Adjusted for age

8.63 (1.77–42.13)

0.01

 Adjusted for male sex

5.85 (1.26–27.29)

0.02

 Adjusted for GPA versus no GPA

5.92 (1.17–30.00)

0.03

 Adjusted for BVAS/WG

5.48 (1.18–25.39)

0.03

  1. Six patients were excluded from the survival analyses since they had already started renal replacement therapy before the diagnosis AAV and were therefore not at risk. Of these patients, 3 had a prodromal phase ≤22 weeks and 3 patients had a prodromal phase >22 weeks
  2. BVAS/WG Birmingham Vasculitis Activity Score specific for Wegener’s Granulomatosis, CI confidence interval, ESRD end-stage renal disease, GPA, granulomatosis with polyangiitis, HR hazard ratio