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Table 1 Baseline patient characteristics (post-randomisation) and changes in TKV and eGFR, as observed in the placebo arm of TEMPO 3:4 study [12, 39]

From: A model to predict disease progression in patients with autosomal dominant polycystic kidney disease (ADPKD): the ADPKD Outcomes Model

 

Placebo arm

(N = 484)

Male gender (n, %)

251 (51.9)

TKV (mL)

 Baseline (mean, SD)

1667.5 (873.1)

 Annual change (mean, SD)

114.4 (113.2)

eGFRa

1/SC ([mg/mL]−1)

CKD-Epi (mL/min/1.73 m2)

 Baseline (mean, SD)

104.30 (33.87)

82.14 (22.73)

 Annual change (mean, SD)

−3.682 (6.361)

−3.568 (4.495)

  1. 1/SC reciprocal of serum creatinine, CKD-Epi Chronic Kidney Disease Epidemiology Collaboration, eGFR estimated glomerular filtration rate, SD standard deviation, TKV total kidney volume
  2. aeGFR was measured using both the reciprocal of serum creatinine (1/SC) and Chronic Kidney Disease Epidemiology Collaboration (CKD-Epi) equation [12]