Table 3 Coefficient estimates for the TKV progression equation (Eq. 1), as derived from TEMPO 3:4 patient-level TKV data
Coefficient estimate | SE | t value | Pr(>|t|) | |
|---|---|---|---|---|
Intercept (λ) | 0.7889 | 1.1313 | 0.697 | 0.4860 |
Age (years) (α) | 0.1107 | 0.0287 | 3.858 | 0.0001 |
Ln(Baseline TKV) (β) | 0.8027 | 0.1556 | 5.159 | 0.0000 |
Sex (female = 1, male = 0) (γ) | −0.0486 | 0.0266 | −1.827 | 0.0684 |
Age:Ln(Baseline TKV) (δ) | −0.0160 | 0.0039 | −4.058 | 0.0001 |