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Table 3 Laboratory data and immunologic profile of the four major primary glomerulonephritides (n = 530)

From: Distribution of glomerular diseases in Taiwan: preliminary report of National Renal Biopsy Registry–publication on behalf of Taiwan Society of Nephrology

 

MCD (n = 114)

FSGS (n = 133)

MGN (n = 127)

IgAN (n = 156)

P value

Hemoglobin, g/dL

13.6 ± 2.3

12.4 ± 2.3

12.3 ± 2.3

12.5 ± 2.4

<0.001

C3, mg/dL

116.1 (96.1–138.0)

111.5 (90.9–133.7)

106.0 (94.0–126.0)

108.5 (92.4–125.6)

0.14

C4, mg/dL

28.1 (23.2–37.6)

28.6 (23.3–33.5)

27.9 (21.4–36.2)

25.6 (20.3–30.6)

0.03

IgG, mg/dL

622.0 (337.0–899.7)

925.5 (626.7–1235.0)

632.0 (449.0–834.0)

1126.0 (938–1366)

<0.001

IgA, mg/dL

260.4 (201.0–360.5)

288.5 (233.0–380.2)

267.0 (213.5–374.2)

369 (278.0–469.5)

<0.001

IgM, mg/dL

121.0 (82.4–173.5)

92.9 (65.4–130.0)

100.5 (64.1–132.5)

103.0 (73.4–140.0)

0.007

IgE, mg/dL

194.3 (30.5–573.0)

68.7.0 (23.3–245.5)

55.4 (23.2–207.0)

64.0 (19.3–173.0)

0.04

Cr, mg/dL

1.0 (0.7–1.6)

1.5 (0.9–2.5)

0.9 (0.7–1.7)

1.2 (0.8–2.1)

<0.001

eGFR, ml/min/1.73m2

78.1 (47.2–118.3)

63.7 (29.7–90.1)

81.3 (56.9–125.3)

59.4 (29.8–89.8)

0.03

Proteinuria, g/day

7.1 (2.5–12.5)

3.3 (1.5–7.6)

6.3 (4.0–10.7)

1.5 (0.6–2.9)

<0.001

Hematuria (n, %)

58 (50.8)

78 (58.6)

77 (60.6)

113 (72.4)

0.02

  1. eGFR estimated glomerular filtration rate, calculated by MDRD equation. Continues variable are represented by mean ± SD or median (interquartile range). Categorical variables are shown as frequency (%)