Existing creatinine-based equations overestimate glomerular filtration rate in Indians

BMC Nephrology

Table 3 Performance of GFR estimating equations as compared to measured GFR by urinary inulin clearance

eGFR equation	Bias (mGFR-eGFR) (ml/min/1.73m²)	95% Limits of agreement (ml/min/1.73m²)	Precision (95% CI) (ml/min/1.73m²)	Accuracy
eGFR equation	Bias (mGFR-eGFR) (ml/min/1.73m²)	95% Limits of agreement (ml/min/1.73m²)	Precision (95% CI) (ml/min/1.73m²)	RMSE (ml/min/1.73m²)	P₃₀ (%)
CKD-EPI_Cr	−24.92 ± 17.17	−58.57 to 8.73	−27.90 to −21.95	30.22	22.3
CKD-EPI (PK)	−16.84 ± 15.39	−47.00 to 13.32	−19.52 to −14.17	47.72	39.2
CKD-EPI (JAP)	−10.62 ± 13.07	−36.22 to 15.02	−12.87 to −8.33	16.79	51.5
MDRD	−26.13 ± 22.74	−73.95 to 28.47	−30.09 to −22.17	34.63	25.4
CKD-EPI_Cys	−3.53 ± 14.70	−32.34 to 25.28	−0.608 to −0.98	15.06	74.6

CKD-EPI Chronic Kidney Disease Epidemiology Collaboration, CI confidence interval, Cys cystatin C, eGFR estimated glomerular filtration rate, F female, JAP Japan, M male, MDRD Modification of Diet in Renal Disease, mGFR measured GFR, PK Pakistan, P₃₀ percentage of participants with eGFR within ±30% of mGFR, RMSE root mean square error

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