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Fig. 5 | BMC Nephrology

Fig. 5

From: Epoetin beta pegol for treatment of anemia ameliorates deterioration of erythrocyte quality associated with chronic kidney disease

Fig. 5

Intracellular calcium level in erythrocytes. a Intracellular calcium level as assessed by Fluo-3/AM intensity was significantly increased in erythrocytes in the UNX-Thy1 + Vehicle group compared with those in the Sham group. C.E.R.A. treatment in the UNX-Thy1 group significantly decreased intracellular calcium level to nearly the same level as in the Sham group. b A significant negative correlation was observed between intracellular calcium level in erythrocytes and erythrocyte deformability. Values are shown as mean ± SEM. *, P < 0.05 (a, Tukey’s test; b, Pearson’s correlation test). Sham, n = 5; UNX-Thy1 + Vehicle, n = 6; UNX-Thy1 + C.E.R.A., n = 6

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