Table 1 Clinical characteristics of patients at presentation and 3 month follow up. Figures are presented as Number (%), mean (SD) and median (IQR)
From: Proteinuric kidney disease in children at Queen Elizabeth Central Hospital, Malawi
Parameter (Reference range) | All Patients | Nephrotic Syndrome | Nephritic Syndrome | CKD | Obstructive Uropathy |
|---|---|---|---|---|---|
(n = 34) | (n = 15) | (n = 10) | (n = 6) | (n = 3) | |
Age, years | 8.5 (3.6) | 8.4 (3.8) | 7.9 (2.6) | 11.4 (1.5) | 6.0 (6.6) |
Gender | |||||
Male | 22 (65%) | 7 (47%) | 8(80%) | 4 (67%) | 3 (100%) |
Female | 12 (35%) | 8 (53%) | 2 (20%) | 2 (33%) | 0 (0%) |
HIV status | |||||
HIV negative | 30 (88%) | 13 (87%) | 9 (90%) | 5 (83%) | 3 (100%) |
HIV unknown | 4 (12%) | 2 (13%) | 1 (10%) | 1(17%) | 0 (0%) |
Albumin (35-50 mg/dl) | |||||
Baseline | 21 (13–29) | 13 (8–16) | 25 (22–28) | 25 (22–27) | 30 (27–33) |
3 months | 33 (21–44) | 36 (18–43) | 38 (30–39) | 31 (0) | 39 (33–45) |
Creatininea (0.2–1.1 mg/dl) | |||||
Baseline | 0.9 (0.6–2.8) | 0.6 (0.3–1.5) | 0.8 (0.6–1.7) | 8.0 (7.1–11.9) | 2.8 (0.86–3.7) |
3 months | 0.8 (0.3–1.0) | 0.9 (0.2–1.0) | 0.6 (0.3–1.0) | 10.5 (0) | 0.7 (0.6–1.4) |
eGFRa(65–135 ml/min/1.73m2) | |||||
Baseline | 47 (26–108) | 100 (47–175) | 41 (33–95) | 6 (4–9) | 29 (10–46) |
3 months | 76 (56–220) | 95 (73–275) | 116 (49–164) | – | 57 (56–67) |
Hypertension | 19 (56%) | 7 (47%) | 7 (70%) | 4 (67%) | 1 (33%) |
Schistosoma antigen positive | 9 (26%) | 5 (33%) | 1 (18%) | 2 (33%) | 1 (33%) |
Malaria positive | 6 (18%) | 0 (0%) | 3 (27%) | 3 (50%) | 0 (0%) |