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Fig. 3 | BMC Nephrology

Fig. 3

From: Phosphate stimulates myotube atrophy through autophagy activation: evidence of hyperphosphatemia contributing to skeletal muscle wasting in chronic kidney disease

Fig. 3

Phosphate overload is associated with increased autophagy. a Western blots show the ratio of LC3II/I increasing in a dose- and time-dependent manner, while p62 protein decreases, indicating autophagy upregulation. b mRNA levels of p62 and LC3 increase with increased phosphate treatment time. Data are shown as fold change compared with the control group (3 mM at 0 h). *p < 0.05 versus 3 mM at 0 h

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BMC Nephrology

ISSN: 1471-2369

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