Fig. 4From: Phosphate stimulates myotube atrophy through autophagy activation: evidence of hyperphosphatemia contributing to skeletal muscle wasting in chronic kidney diseaseBlockage of autophagy attenuated high Pi-induced cell atrophy in L6 cells. a Western blot shows the ratio of LC3II/I decreases with wortmannin or pLKO.1-EGFP-Atg5 (Atg5 −/−) treatment and increases with CD513B-1-Atg5 (Atg5) treatment. b Cell diameter with different treatments. Data are shown as fold change compared with the control group (3 mM, 24 h). *p < 0.05 versus controlBack to article page