Table 1 Baseline characteristics

Number

67

25

Age, years (mean ± SD)

68 ± 14

65 ± 15

NS

Female gender, n (%)

19 (28)

11 (44)

NS

Hypertension, n (%)

43 (64)

15 (60)

NS

Diabetes, n (%)

21 (31)

6 (24)

NS

Baseline creatinine level, mg/dl (mean ± SD)

0.97 ± 0.38

0.98 ± 0.41

NS

Chronic kidney disease^a, n (%)

19 (28)

5 (20)

NS

 Cardiovascular disease, n (%)

18 (27)

5 (20)

NS

 Infection, n (%)

10 (15)

6 (24)

NS

 Neurological disease

5 (7)

2 (8)

NS

  Liver failure

1 (1)

3 (12)

NS

  Kidney failure

2 (3)

1 (4)

NS

  Surgery

31 (46)

8 (32)

NS

Time from ICU admission to day 1, days (median (IQR))

1 (IQR1-3)

1 (IQR 1-12)

NS

Patients with SIRS on day 1, n (%)

42 (63)

19 (76)

NS

Patient with SIRS and infection on day 1, n (%)

6 (9)

6 (24)

NS

APACHE 2 score on admission, (mean ± SD)

27 ± 7

32 ± 7

<  0.005

SOFA score^b on day 1, (mean ± SD)

9 ± 4

12 ± 4

<  0.005

Patients under vasoactive drugs, n (%)

42 (63)

18 (72)

NS

Invasive ventilation, n (%)

47 (70)

20 (80)

NS

Creatinine on day 1, mg/dl (mean ± SD)

0.97 ± 0.38

0.98 ± 0.41

NS

Oliguria^c on day 1, n (%)

7 (10)

3 (12)

NS

Hemoglobin on day 1, g/dl (mean ± SD)

108 ± 16

99 ± 20

< 0.05

Thrombocyte count on day 1, x 109/l (mean ± SD)

188 ± 98

130 ± 88

< 0.05

C reactive protein on day 1, mg/l (mean ± SD)

14 ± 10

12 ± 11

NS