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Table 3 Multivariable linear regression analysis presenting associations between klotho and pulse wave velocity

From: The association between soluble klotho and cardiovascular parameters in chronic kidney disease: results from the KNOW-CKD study

  Variable Model A Model B Model C
   β (95% CI) P- value β (95% CI) P- value β (95% CI) P- value
baPWV Klotho (pg/mL) −0.011 (− 0.07, 0.04) 0.582 −0.017 (− 0.07, 0.02) 0.329 0.003 (− 0.04, 0.05) 0.876
hfPWV Klotho (pg/mL) −0.029 (− 0.09, 0.02) 0.228 − 0.037 (− 0.09, 0.01) 0.087 −0.013 (− 0.06, 0.034) 0.564
  1. Model A: Adjusted for klotho, age and gender
  2. Model B: Adjusted for klotho, age, gender, DM, HTN, BMI, and SBP
  3. Model C: Adjusted forklotho, age, gender, DM, HTN, BMI, SBP, eGFR, hemoblogin, phosphorus, corrected Ca, and FGF23
  4. β Standardized coefficient, CI confidence interval, baPWV brachial-to-ankle pulse wave velocity; hfPWV, heart-to-femoral pulse wave velocity; DM diabetes mellitus, HTN hypertension, BMI body mass index, SBP systolic blood pressure, eGFR estimated glomerular filtration rate by CKD-EPI creatinine equation, Ca calcium, FGF23 fibroblast growth factor 23