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Table 1 Basic parameters

From: Expression of brain-derived neurotrophic factor in kidneys from normal and cyclosporine-treated rats

 

VH (n = 8)

CsA (n = 8)

Body Weight (g)

353.9 ± 12.3

281 .2 ± 11.1*

Water Intake (mL)

15.3 ± 4.6

20.2 ± 4.5*

Urine Volume (mL)

10.3 ± 2.1

23.9 ± 6.2*

Urine BDNF (pg/mL)

0.06 ± 0.002

3.62 ± 1.02*

Urine 8-OHdG (ng/day)

303.9 ± 41.3

120.7 ± 27.0

Serum 8-OHdG (ng/mL)

82.9 ± 11.8

40.9 ± 7.5

BUN (mg/dL)

14.2 ± 2.4

47.3 ± 11.4*

Scr (mg/dL)

0.6 ± 0.1

0.9 ± 0.3*

SBP (mmHg)

124.2 ± 4.1

128.7 ± 11.3

CsA con. (ng/mL)

0 ± 0

1922.7 ± 22.3*

  1. Values are means ± SEM. VH vehicle, CsA cyclosporine A, BDNF brain-derived neurotrophic factor, 8-OHdG 8-hydroxy-2′-deoxyguanosine, BUN blood urea nitrogen, Scr serum creatinine, SBP systolic blood pressure. *p < 0.05 vs. VH