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Table 3 Cox proportional hazards model for the association of baseline measures of proteinuria and individual (secondary) outcomes

From: Predictive value of spot versus 24-hour measures of proteinuria for death, end-stage kidney disease or chronic kidney disease progression

 

Univariable model

Multivariable model

 

Death

ESKD

>  30% decline in eGFR

Death

ESKD

> 30% decline in eGFR

Log UPCR

1.42 (1.05–1.92)

p = 0.02

1.48 (1.18–1.88)

p = 0.001

1.34(1.01–1.77)

p = 0.04

1.18 (0.96–1.84)

p = 0.3

1.27 (0.97–1.66)

p = 0.08

1.29 (0.97–1.71)

p = 0.09

Log UACR

1.26 (0.99–1.60)

p = 0.06

1.42 (1.17–1.73)

p < 0.001

1.36 (1.00–1.55)

p = 0.06

1.19 (0.92–1.55)

p = 0.2

1.33 (1.07–1.66)

p = 0.009

1.21 (0.98–1.50)

p = 0.08

Log 24-h protein excretion

1.28 (0.94–1.73)

p = 0.1

1.47 (1.17–1.85)

p = 0.001

1.62 (1.20–2.19)

p = 0.002

1.19 (0.83–1.71)

p = 0.3

1.39 (1.07–1.82)

p = 0.02

1.54 (1.13–2.09)

p = 0.005

  1. The multivariable model was adjusted for age, baseline eGFR, diabetes mellitus and hypertension
  2. UPCR urine protein-to-creatinine ratio, UACR urine albumin-to-creatinine ratio, ESKD end-stage kidney disease, eGFR estimated glomerular filtration rate
  3. ESKD is defined as the requirement for dialysis or pre-emptive kidney transplantation