Table 2 Sex differences in the incidence and severity of autoimmune diseases
SLE | RA | SS | ||
|---|---|---|---|---|
Peak Incidence | Reproductive age | Perimenopausal | After 50-60 years | |
Female/Male Ratio | Peak 15:1 | Peak 4:1 | Peak 14:1 | |
Total 9:1 | After 60 years 1:1 | Total 3:1 | ||
Influence of Estrogen | High levels | Negative | Positive | ? |
Low levels | ? | Negative | Negative | |