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Table 2 Sex differences in the incidence and severity of autoimmune diseases
| SLE | RA | SS | ||
|---|---|---|---|---|
| Peak Incidence | Reproductive age | Perimenopausal | After 50-60 years | |
| Female/Male Ratio | Peak 15:1 | Peak 4:1 | Peak 14:1 | |
| Total 9:1 | After 60 years 1:1 | Total 3:1 | ||
| Influence of Estrogen | High levels | Negative | Positive | ? |
| Low levels | ? | Negative | Negative | |
