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Table 8 Treatment effect of dialysate to serum sodium alignment on volume-related and hemodynamic parameters in those patients part to this quality initiative (as-treated cohort; N = 137) and the propensity score matched control cohort (N = 137)

From: Effects of dialysate to serum sodium (Na+) alignment in chronic hemodialysis (HD) patients: retrospective cohort study from a quality improvement project

Parameter

Study Regimen

Baseline

Follow-up

Difference (95% CI)

Treatment effect (95% CI)

Pre HD SBP [mmHg]

aligned

143.42+/−21.27

143.06+/−21.2

−0.36 (−5.41 to 4.69)

1.68 (−0.87 to 4.23)

unaligned

146.94+/−20.88

144.9+/−22

−2.04 (−7.15 to 3.07)

Post HD SBP [mmHg]

aligned

132.8+/−16.83

133.36+/−17.68

0.56 (−3.55 to 4.67)

1.43 (−0.86 to 3.72)

unaligned

137.57+/−19.27

136.7+/−19.7

−0.87 (−5.5 to 3.76)

Pre HD DBP [mmHg]

aligned

73.23+/−13.03

72.99+/−12.65

−0.24 (−3.3 to 2.81)

0.43 (−0.94 to 1.8)

unaligned

75.9+/−12.16

75.2+/−12.1

−0.67 (−3.56 to 2.21)

Post HD DBP [mmHg]

aligned

68.14+/−9.59

68.23+/−10.13

0.09 (−2.26 to 2.44)

0.34 (−0.91 to 1.58)

unaligned

70.97+/−10.62

70.7+/−10.3

−0.25 (−2.74 to 2.24)

Pre HD PP [mmHg]

aligned

70.19+/−15.3

70.07+/−15.6

−0.12 (−3.79 to 3.56)

1.25 (−0.4 to 2.9)

unaligned

71.05+/−15.24

69.7+/−15.9

−1.37 (−5.07 to 2.34)

Post HD PP [mmHg]

aligned

64.66+/−13.4

65.13+/−13.7

0.47 (−2.75 to 3.69)

1.09 (−0.38 to 2.57)

unaligned

66.59+/−13.91

66+/−14.4

−0.62 (−4 to 2.75)

Pre HD MAP [mmHg]

aligned

96.63+/−14.56

96.35+/−14.23

−0.28 (−3.71 to 3.14)

0.85 (−0.83 to 2.52)

unaligned

99.58+/−13.86

98.5+/−14.3

−1.13 (−4.47 to 2.22)

Post HD MAP [mmHg]

aligned

89.7+/−10.76

89.94+/−11.44

0.25 (−2.4 to 2.89)

0.7 (−0.82 to 2.22)

unaligned

93.17+/−12.49

92.7+/−12.4

−0.45 (−3.41 to 2.51)

Intra HD SBP change [mmHg]

aligned

−10.61+/−13.72

−9.7+/−14.67

0.92 (−2.46 to 4.3)

−0.25 (−2.65 to 2.14)

unaligned

−9.38+/−14.23

−8.2+/−14.7

1.17 (−2.27 to 4.61)

Intra HD DBP change [mmHg]

aligned

−5.09+/−6.8

−4.76+/−7.3

0.33 (−1.34 to 2.01)

−0.09 (−1.24 to 1.05)

unaligned

−4.92+/−6.98

−4.5+/−7

0.43 (−1.23 to 2.09)