Table 3 Unadjusted and multivariable adjusted Odd Ratios and 95% confidence intervals for Central Venous Catheter use (vs Fistula)
Variable | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 |
|---|---|---|---|---|---|
Dialysis Centre | |||||
Centre 1 (Referent) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Centre 2 | 2.01 (1.08–3.75) * | 1.86 (0.99–3.50) | 1.91 (1.00–3.65)* | 1.98 (1.02–3.81)* | 1.98 (1.02–3.84)* |
Centre 3 | 0.88 (0.59–1.30) | 0.85 (0.57–1.26) | 0.77 (0.51–1.16) | 0.83 (0.54–1.26) | 0.79 (0.51–1.24) |
Centre 4 | 2.56 (1.55–4.25) *** | 2.59 (1.55–4.33)*** | 2.59 (1.53–4.37)*** | 2.61 (1.54–4.43)*** | 2.86 (1.67–4.90)*** |
Centre 5 | 0.73 (0.45–1.18) | 0.69 (0.42–1.14) | 0.71 (0.43–1.18) | 0.72 (0.43–1.20) | 0.79 (0.47–1.33) |
Centre 6 | 0.95 (0.57–1.60) | 0.96 (0.57–1.63) | 0.87 (0.51–1.50) | 0.91 (0.52–1.58) | 0.60 (0.32–1.11) |
Centre 7 | 1.51 (0.94–2.43) | 1.41 (0.87–2.29) | 1.36 (0.83–2.24) | 1.47 (0.88–2.45) | 1.18 (0.69–2.01) |
Centre 8 | 1.32 (0.87–2.00) | 1.36 (0.89–2.07) | 1.23 (0.79–1.91) | 1.18 (0.75–1.85) | 1.31 (0.83–2.06) |
Centre 9 | 0.88 (0.54–1.42) | 0.83 (0.51–1.36) | 0.74 (0.45–1.23) | 0.81 (0.48–1.35) | 0.86 (0.51–1.45) |
Centre 10 | 1.02 (0.62–1.68) | 0.98 (0.59–1.62) | 0.87 (0.52–1.47) | 0.90 (0.53–1.52) | 0.97 (0.57–1.66) |
Demographic Factor | |||||
Female (vs male) | 1.68 (1.31–2.15)**** | 1.79 (1.39–2.31)**** | 1.87 (1.44–2.43)**** | 1.77 (1.34–2.34)**** | |
Age group (years) | |||||
< 65 (Ref) | 1.00 | 1.00 | 1.00 | 1.00 | |
65–74 | 1.30 (0.97–1.74) | 1.20 (0.89–1.62) | 1.19 (0.87–1.61) | 1.05 0.76–1.45) | |
≥ 75 | 1.46 (1.10–1.94)** | 1.41 (1.05–1.89)* | 1.35 (1.00–1.83) | 1.15 (0.83–1.60) | |
Lifestyle factor | |||||
Body mass index (BMI) group (kg/m2) | |||||
< 20 | 1.74 (0.91–3.36) | 1.81 (0.93–3.53) | 1.86 (0.95–3.62) | 1.78 (0.91–3.50) | |
20–25 (Ref) | 1.00 | 1.00 | 1.00 | 1.00 | |
25–30 | 0.81 (0.60–1.09) | 0.77 (0.57–1.04) | 0.75 (0.55–1.02) | 0.77 (0.56–1.05) | |
> 30 | 0.82 (0.60–1.13) | 0.73 (0.52–1.02) | 0.73 (0.52–1.03) | 0.76 (0.54–1.08) | |
Vintage (years) | |||||
< 1 (Ref) | 1.00 | 1.00 | 1.00 | ||
1–4 | 0.45 (0.31–0.65)**** | 0.46 (0.31–0.67)**** | 0.48 0.33–0.71)*** | ||
> 4 | 0.36 (0.24–0.52)**** | 0.39 (0.26–0.57)**** | 0.40 (0.26–0.60)**** | ||
Comorbid conditions | |||||
Atherosclerotic heart disease (yes vs no) | 1.13 (0.81–1.56) | 1.11 (0.80–1.55) | 1.09 (0.78–1.52) | ||
Diabetes (yes vs no) | 1.40 (1.06–1.86)* | 1.50 (1.02–2.23)* | 1.38 (0.93–2.06) | ||
Hypertension (yes vs no) | 0.78 (0.60–1.01) | 0.85 (0.65–1.11) | 0.86 (0.65–1.13) | ||
Primary cause of kidney disease | |||||
Glomerulonephritis (Referent group) | 1.00 | 1.00 | |||
Cystic kidney disease | 0.37 (0.21–0.67)*** | 0.38 (0.21–0.68)** | |||
Diabetes | 0.84 (0.50–1.41) | 0.85 (0.50–1.43) | |||
Hypertension | 0.77 (0.46–1.30) | 0.83 (0.49–1.41) | |||
Other cause | 1.05 (0.65–1.70) | 1.03 (0.63–1.69) | |||
Other urologic | 1.15 (0.71–1.85) | 1.13 (0.70–1.85) | |||
Unknown/missing | 1.29 (0.89–1.87) | 1.30 (0.89–1.90) | |||
Laboratory values | |||||
Albumin (per 5 g/L) | 0.73 (0.59–0.90)** | ||||
Pre-dialysis Creatinine (per 50 μmol/L) | 0.99 (0.96–1.03) | ||||
Model performance | |||||
C-Statistic | 0.59 | 0.64 | 0.67 | 0.68 | 0.69 |
P value of Centre variable | 0.0002 | 0.0002 | 0.0001 | 0.0003 | 0.0001 |
ANOVA p value for model with and without Centre variable | – | 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |