Predominant but silent C1q deposits in mesangium on transplanted kidneys - long-term observational study

BMC Nephrology

Table 1 Clinical and pathologic findings at the time when predominant mesangial C1q deposits were detected

Case No.	Reason for RBx	Laboratory results			LM findings	IF findings					EM findings
Case No.	Reason for RBx	Up	OB	sCr [mg/dL]		IgG	IgM	IgA	C1q	C3	Mes	Subend	Subep	ARB
1	Protocol	(−)	(−)	0.7	MGA	2+	1+	1+	2+	1+	(+)	(−)	(+)	–
2	Protocol	(+)	(−)	0.6	MGA	2+	1+	–	2+	1+	(+)	(−)	(−)	losartan potassium 100 mg/day
3	Protocol	(−)	(−)	1.2	MGA	2+	1+	–	2+	1+	(+)	(+)	(−)	–
4	Mild proteinuria	(+)	(−)	0.7	MGA	2+	2+	–	2+	1+	(+)	(−)	(−)	–
5	Protocol	(−)	(−)	0.6	MGA	1+	1+	–	2+	1+	(+)	(−)	(+)	losartan potassium 25 mg/day

Abbreviation: No number, RBx renal biopsy, LM light microscopy, IF immunofluorescent, EM electron microscopy, Up urinary protein, OB occult blood, sCr serum creatinine, MGA minor glomerular abnormality, Mes mesangial deposits, subend subendothelial deposits, Subep subepithelial deposits

ISSN: 1471-2369