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Table 2 Laboratory parameters at time 0 (admission) and at 36 h, intended as means and standard deviation (SD); EB (excess of bases), pCO2 (CO2 partial blood pressure)

From: Metformin associated lactic acidosis: a case series of 28 patients treated with sustained low-efficiency dialysis (SLED) and long-term follow-up

Laboratory parameters at time 0 (admission) and at 36 h, intended as means and standard deviation (SD)

Variable (mean ± SD)

Time 0

Time 1 (36 h)

Sig.

Serum Creatinine (mg/dl)

8.1 ± 3.1

5.3 ± 2.8

p < 0.05

Blood Urea Nitrogen (mg/dl)

96.8 ± 47.4

54.6 ± 27.4

p < 0.05

Hemoglobin (g/dl)

10.7 ± 1.6

11.2 ± 1.8

p NS

Potassium (mEq/L)

5.93 ± 1.4

4.03 ± 0.8

p < 0.05

Glycemia (mg/dl)

178.8 ± 123

160.1 ± 24

p NS

C-reactive protein (mg/dl)

8.6 ± 8.9

4.3 ± 2.3

p < 0.05

pH, serum

7.01 ± 0.22

7.35 ± 0.7

p < 0.05

HCO3 -(mmol/L)

7.72 ± 4.4

22.7 ± 6.4

p < 0.05

EB (mmol/L)

−19.3 ± 11.7

−1.92 ± 5.6

p < 0.05

Lactate (mmol/L)

13.7 ± 6

2.6 ± 2.6

p < 0.05

Anion gap (mmol/L)

36.2 ± 8.2

13.2 ± 4.1

p < 0.05

VpCO2 (mEq/L)

25.7 ± 9.5

39.1 ± 4.4

p < 0.05

VpO2 (mEq/L)

65.4 ± 10.5

42.4 ± 9.9

p < 0.05