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Table 1 Summary of studies estimating CKD prevalence in the UK [1421]

From: An ontological approach to identifying cases of chronic kidney disease from routine primary care data: a cross-sectional study

Publication(s)

Cohort

Determination of CKD

Prevalence of

CKD stages 3–5

Stevens 2007

130,266 patients from GP practices in Kent, Manchester and Surrey, aged 18 and over

Single eGFR (MDRD) determined from calibrated creatinines

8.5%

de Lusignan 2011,

Kearns 2013

Up to 930,977 patients from practices in the Quality Improvement in CKD study (QICKD), aged 18 and over

Various methods including single and multiple eGFR readings (MDRD and CKD-EPI)

4.8–6.8%

Roderick 2011,

Fraser 2015

Data from the Health Survey for England 2009–2010, involving more than 6000 participants, aged 16 and over

Single eGFR reading (MDRD and CKD-EPI) in combination with urine estimation of albuminuria

5.2–6.0%

Jameson 2014

Approximately 2.8 million individuals in the General Practice Research Database (GPRD), aged 18 and over

Two laboratory eGFR readings at least 90 days apart (MDRD) and Read diagnostic codes

5.9%

Jain 2014

Data from The Health Improvement Network (THIN) database, comprising 2,707,130 patients from 426 GP practices, aged 18 and over

2 most recent laboratory eGFR readings taken at least 7 days apart (MDRD) and Read diagnostic codes

4.0%

NCKDA 2016

Data from 911 GP practices from England and Wales, encompassing 5.2 million adults

Two eGFR calculations at least 90 days apart (MDRD), Read diagnostic codes

5.5%

  1. NCKDA National CKD Audit, GP general practitioner, CKD Chronic kidney disease, eGFR Estimated glomerular filtration rate