Table 2 Visit schedule for REMOVAL-HD study

 Inclusion/exclusion criteria

X

X

 Informed Consent

X

 24 h Urine collection

X

 Demographics/Medical History/Physical exam

X

 Centrally tested serum albumin^a

X

X

X

X

X

X

X

X

X

X

 High Flux (Revaclear) dialyser

X

X

X

X

 Mid cut-off (Theranova) dialyser

X

X

X

X

X

X

X

X

 Erythropoietin Resistance Index

X

X

X

 Weight (pre & post HD)

X

X

X

X

 Duration of HD

X

X

X

X

 Restless Leg Symptom Rating Scale

X

X

X

 Malnutrition Inflammation Score

X

X

X

 Edmonton Symptom Assessment System Revised

X

X

X

 6 min walk test^a

X

X

X

 Adverse events (as required)

X

X

X

X

X

X

X

X

X

X

 Albumin^a

X

X

X

X

X

X

X

X

X

X

 Urea (pre & post HD)

X

X

X

 Haemoglobin, transferrin, INR, APTT^a

X

X

X

 Lambda free light chains^a

X

X

X

X

X

X

X

X

X

X

 Κappa-FLC, β2Microglobulin, high sensitivity C-Reactive Protein^a

X

X

X

 Substudy – Matrix Gla Protein, fetuin A, CPP, FGF23^a

X

X

X