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Table 2 Characteristics of late de novo DSA (dnDSA)

From: Clinical and histological evolution after de novo donor-specific anti-human leukocyte antigen antibodies: a single centre retrospective study

 

Patients with late dnDSA (n = 22)

Time from kidney transplantation to dnDSA in years; mean (SD)

10 (7.5)

HLA class (n, %)

Class I

1 (4.5)

Class II

15 (68.1)

Class I + II

6 (27.0)

MFI mean (SD)

5896 (3879)

Triple immunosuppression 1 year post-Tx (n, %)

18 (81.8)

Triple immunosuppression at the time of dnDSA (%)

5 (22.7)

AKI at the time of dnDSA (n, %)

4 (18.2)

Mean eGFR using the CKD-EPI equation in ml/min (+/− SD)

45.9 (16.7)

Albuminuria at the time of dnDSA diagnosis (n, %)

12 (54.5)

  1. MFI mean fluorescence intensity, Tx transplantation, AKI acute kidney injury, eGFR estimated glomerular filtration rate, CKD-EPI Chronic Kidney Disease Epidemiology Collaboration, SD standard deviation