Biopsy at the time of dnDSA | Follow up biopsy | Paired t-test | |
---|---|---|---|
Mean eGFR using the CKD-EPI equation (ml/min, mean +/− SD) | 45.9 (16.7) | 37.4 (13.8) | 0.005 |
g (n, % of g ≥ 1) | 10 (45.4) | 11 (50.0) | 0.47 |
ptc (n, % of ptc ≥ 1) | 10 (45.4) | 6 (27.2) | 0.26 |
g + ptc (n, % of g + ptc ≥ 2) | 10 (45.4) | 7 (31.8) | 0.77 |
Overall change in g + ptc (n, %) | |||
○ Reduction in g + ptc score | 9 (40.9) | ||
○ No change in g + ptc score | 7 (31.8) | ||
○ Progression in g + ptc score | 6 (27.3) | ||
t (n, % of t ≥ 1) | 4 (18.1) | 0 | 0.04 |
C4d (n, % of c4d ≥ 1) | 9 (40.9) | 5 (22.7) | 0.16 |
cg (n, % of cg ≥ 1) | 6 (27.2) | 10 (45.4) | 0.04 |