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Table 4 Overall effect of treatment on the evolution eGFR, microvascular inflammation (MVI) and chronic transplant glomerulopathy (cg); Fisher’s exact test p = 0.64, 0.86 and 1.0, respectively

From: Clinical and histological evolution after de novo donor-specific anti-human leukocyte antigen antibodies: a single centre retrospective study

 

No treatment at the time of dnDSA (n = 9)

Any combination of treatment at the time of dnDSA (n = 13)

eGFR evolution

eGFR increase

3

4

Stable eGFR

1

0

eGFR decrease

5

9

MVI evolution

MVI reduction

3

6

No change in MVI

3

4

MVI progression

3

3

Cg evolution

Cg reduction

1

0

No change in cg

5

11

Cg progression

3

2

  1. eGFR estimated glomerular filtration rate, CKD-EPI Chronic Kidney Disease Epidemiology Collaboration, MVI microvascular inflammation defined as the g + ptc score