Fig. 3

Levels of Cur according to CKD, hypertension, and albuminuria status. Levels of Cur were compared among different groups in CKD stages (a), hypertension status (b), and albuminuria status (c) using a multivariate analysis. Compared with stage 1 CKD, Cur decreased in stage 3–5 CKD (a). The level of Cur was lower in stage 1–3 hypertension than that in normo-tension group (b). Furthermore, participants in the macro-albuminuria group had significantly lower Cur compared with those in the normo-albuminuria group (c). a Cur in CKD stage1–5; (b) Cur in H0: normo-tension; H1: stage 1 hypertension; H2: stage 2 hypertension; H3: stage 3 hypertension; (c) Cur in A1: UACR< 3 mg/mmol, normo-albuminuria; A2: 3 ≤ UACR≤30 mg/mmol, microalbuminuria; A3: UACR> 30 mg/mmol, macro-albuminuria. Error bars represent the standard deviation values. * P < 0.05, ** P < 0.01 vs. CKD1, H0, A1 respectively. Abbreviations: Cur, uric acid clearance rate; UACR, urinary albumin to creatinine ratio; CKD, chronic kidney disease