Table 1 Body weight, plasma markers and kidney function

n

9

10

10

Body weight (g)

232 ± 3.6

223 ± 1.6*

241 ± 4.2^††

Left kidney weight (g)

0.75 ± 0.09

1.15 ± 0.07***

1.01 ± 0.51^†††

Left kidney /body weight (g/100 g)

0.24 ± 0.01

0.35 ± 0.01***

0.24 ± 0.003^†††

Plasma ACE activity (nmol/ml/hr)

1474 ± 156

1624 ± 101

13 ± 4^†††

Plasma urea (mmol/l)

5.3 ± 0.2

9.5 ± 0.6***

10.8 ± 0.7

Urine protein (mg/100 g/24 h)

57.2 ± 2.5

91.7 ± 10.7**

66.6 ± 3.2^†

Plasma creatinine (μmol/l)

22 ± 1

45 ± 4***

46 ± 2

Creatinine clearance (ml/min)

2.84 ± 0.20

1.39 ± 0.17***

1.49 ± 0.10