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Table 3 Left ventricular gene expression

From: Left ventricular hypertrophy in experimental chronic kidney disease is associated with reduced expression of cardiac Kruppel-like factor 15

Fold change in mRNA (arbitrary units)

Control

Subtotal nephrectomy (STNx)

Vehicle

Vehicle

Ramipril

n

9

10

10

Angiotensin converting enzyme

1.00 ± 0.09

0.81 ± 0.08

0.38 ± 0.06††

Atrial natriuretic peptide

1.00 ± 0.26

7.98 ± 2.09**

0.92 ± 0.25††

Brain natriuretic peptide

1.00 ± 0.17

2.97 ± 0.55**

1.16 ± 1.22†

Connective tissue growth factor

1.00 ± 0.17

7.76 ± 0.29*

0.48 ± 0.17††

GATA binding protein 4

1.00 ± 0.09

1.83 ± 0.3*

1.17 ± 0.18

Myocyte enhancer factor 2A

1.00 ± 0.11

1.64 ± 0.29

1.14 ± 0.18

  1. Data are presented as mean ± SEM. Control vs. STNx-vehicle (disease effect) *P < 0.05, **P < 0.01; STNx-vehicle vs. ramipril (treatment effect) †P < 0.05, ††P < 0.01