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Table 1 Baseline characteristics of study participants

From: Determinants of hyperuricemia in non-dialysed chronic kidney disease patients in three hospitals in Cameroon

Variable

Total (N = 103)

Age (years), mean ± SD

55.78 ± 12.58

Age Strata, n (%)

 20–29 years

2 (1.9)

 30–39 years

9 (8.7)

 40–49 years

19 (18.4)

 50–59 years

33 (32.0)

 60–69 years

23 (22.3)

  > 70 years

17 (16.5)

Male gender, n (%)

61 (59.2)

Duration of CKD diagnosis (months), mean ± SD

14.67 ± 18.05

CKD stage, n (%)

 Stage 1/G1

0 (0.0)

 Stage 2/G2

4 (3.9)

 Stage 3a/G3a

8 (7.8)

 Stage 3b/G3b

15 (14.6)

 Stage 4/G4

50 (48.5)

 Stage 5/G5

26 (25.2)

Type of renal involvement, n (%)

 Glomerular

62 (60.2)

 Tubulo-interstitial

12 (11.7)

 Vascular

20 (19.4)

 Mixed

9 (8.7)

Comorbidities, n (%)

 Hypertension

90 (87.4)

 Diabetes

35 (34.0)

 Gout

22 (21.4)

 HIV

13 (12.6)

Dietary regimen, n (%)

 None

32 (31.1)

 Low protein

46 (55.3)

 Low-carb

52 (50.5)

 Low fat

29 (28.2)

Medications, n (%)

 aUrate lowering therapy

42 (40.8)

 bLoop diuretics

32 (31.1)

 cThiazide diuretics

1 (1.0)

 dARB

5 (4.9)

Systolic Blood Pressure (mmHg), mean ± SD

142.3 ± 30.3

Diastolic Blood Pressure (mmHg), mean ± SD

88.3 ± 21.3

Weight (kg), median (IQR)

75.00 (18.40)

Height (m), median (IQR)

1.66 (0.10)

BMI (kg/m2), median (IQR)

26.30 (6.04)

Haemoglobin (g/dl), mean ± SD

10.27 ± 1.76

Total Cholesterol (mmol/l), mean ± SD

2.06 ± 0.56

HDL-c (mmol/l), mean ± SD

0.55 ± 0.19

LDL-c (mmol/l), mean ± SD

1.25 ± 0.42

Tryglycerides (mmol/l), median (IQR)

1.04 (0.72)

Plasma creat (mg/dl), median (IQR)

3.65 (1.55)

eGFR (ml/min per 1.73m2), median (IQR)

17.00 (11.00)

Spot urine protein (mg/dl), median (IQR)

1.07 (1.06)

Spot urine creat (mg/dl), median (IQR)

1.47 (1.14)

Spot urine PCR (mg/g), median (IQR)

803.0 (1120.0)

Serum uric acid (mg/l), mean ± SD

76.19 ± 20.25

Hyperuricemia, n (%)

69 (67.0)

  1. CKD Chronic kidney disease, HIV Human immuno-deficiency virus, ARB Angiotensin receptor blockers, BMI Body mass index, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, Creat Creatinine, eGFR Estimated glomerular filtration rate, PCR Protein-to-creatinine ratio, SD standard deviation, IQR interquartile range
  2. aAllopurinol
  3. bFurosemide
  4. cHydrochlorothiazide
  5. dLosartan