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Table 2 Effect of Fructose with or without Heat on Renal Disease

From: Rehydration with fructose worsens dehydration-induced renal damage

Parameters Control Fructose Heat Heat+F Anova p values
Serum Creatinine (μg/ml) 0.38 ± 0.1 0.36 ± 0.1 0.69 ± 0.2 0.72 ± 0.2 P < 0.001
Urine Albumin (μg/mg of Cr) 26.1 ± 5.1 27.5 ± 7.5 54.3 ± 28.1 65.5 ± 32.3 P < 0.05
ACE Positivity % (proximal tubular brush border integrity) 10.3 ± 2.3 6.6 ± 1.8 6.9 ± 1.6 4.5 ± 3.1 P < 0.0001
Monocyte Accumulation (F4/80) % 0.13 ± 0.3 0.13 ± 0.2 0.25 ± 0.3 0.55 ± 0.6 P < 0.05
Interstitial Fibrosis (Coll-III) % 0.23 ± 0.1 0.28 ± 0.3 0.43 ± 0.3 0.53 ± 0.4 P < 0.0001
  1. Comparisons: The serum creatinine of Control is lower than HEAT (P < 0.05) and HEAT+F group (P < 0.05) by Bonferroni. Fructose has lower serum creatinine than HEAT (P < 0.05) and HEAT+F (P < 0.05). Controls tends to have lower urinary albumin than HEAT+F (P = 0.055) and Fructose tends to be lower than HEAT+F (P = 0.051) by Bonferroni. Controls have more proximal tubular brush border (ACE positivity) than Fructose (P < 0.001), Heat (P < 0.001) and HEAT+F (P < 0.001) by Bonferroni. The Fructose group has more brush border (ACE positivity) than HEAT+F (P < 0.01). The HEAT group has more ACE positivity than HEAT+F group by t test (P < 0.001). Controls have significantly less interstitial macrophage accumulation than HEAT+F (P < 0.05) by Bonferroni. Controls have significantly less interstitial fibrosis than HEAT (P < 0.01) and HEAT+F (P < 0.001) by Bonferroni post hoc test