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Table 1 Baseline characteristics of the patients in the three groups

From: Retrospective analysis of tacrolimus combined with Tripterygium wilfordii polyglycoside for treating idiopathic membranous nephropathy

Characteristics TAC group (n = 33) TAC + MP group (n = 24) TAC + TWG group (n = 21) P value
Sex (male/female) 13/20 14/10 9/12 0.35
Age (years) 40(21) 40(26) 50(22) 0.16
42.00 ± 15.25 43.29 ± 14.59 49.43 ± 11.89  
BMI (kg/m2) 25.30(4.85) 24.85(5.82) 23.70(5.10) 0.37
25.82 ± 5.38 25.91 ± 3.59 24.85 ± 5.05  
Systolic BP (mmHg) 129.15 ± 15.38 131.00 ± 15.65 131.00 ± 20.48 0.93
Diastolic BP (mmHg) 71.73 ± 16.77 71.83 ± 16.14 69.29 ± 15.51 0.62
Daily urinary protein (g/24 h) 6.07(2.43) 7.38(2.87) 5.92(2.19) 0.387
6.95 ± 2.43 7.25 ± 1.61 6.61 ± 1.34  
Serum albumin (g/L) 26.13 ± 3.31 26.07 ± 2.81 25.10 ± 3.55 0.64
Concentrations of anti-PLA2R antibodies (RU/mL) 571.00 (215.00) 571.5(61.25) 641.69(98.00) 0.018*
Anti-PLA2R (positive/negative) 32/1 23/1 20/1 1
Scr (μmol/L) 72.38 ± 19.78 77.28 ± 23.82 69.19 ± 15.53 0.57
BUN (mmol/L) 5.37 ± 1.97 6.46 ± 2.88 6.00 ± 1.78 0.16
UA (μmol/L) 358.28 ± 128.60 326.81 ± 97.13 353.62 ± 110.70 0.47
eGFR (ml/min/1.73 m2) 97.58 ± 25.51 97.44 ± 24.48 98.40 ± 15.85 0.99
Hb (g/L) 128.79 ± 16.42 129.67 ± 17.37 131.33 ± 22.04 0.89
PLT (10^9/L) 252.58 ± 63.37 257.88 ± 60.62 233.86 ± 57.8 0.39
WBC (10^9/L) 7.28 ± 1.74 6.97 ± 1.60 6.70 ± 1.86 0.49
Tch (mmol/L) 5.67 ± 1.95 6.13 ± 2.65 5.56 ± 0.89 0.62
TG (mmol/L) 1.77 ± 2.04 2.41 ± 1.76 2.08 ± 0.85 0.26
LDL (mmol/L) 3.57 ± 1.19 4.46 ± 2.02 3.59 ± 1.02 0.32
HDL (mmol/L) 1.50 ± 0.60 1.55 ± 0.56 1.55 ± 0.73 0.97
Blood glucose (mg/dL) 5.10 ± 0.61 4.9 ± 0.84 6.08 ± 2.38 0.37
Conservative treatment time (months) # 5.00(4.50) 8.00(5.00) 9.00(13.00) 0.06
6.79 ± 2.25 8.54 ± 2.70 9.71 ± 5 .60  
ALT (U/L) 31.33 ± 5.12 33.78 ± 8.01 31.82 ± 5.27 0.33
AST (U/L) 15.72 ± 4.47 17.94 ± 10.75 18.13 ± 4.70 0.16
Glomerular stage at renal biopsy (I/I-II/II/II-III/III) 16/4/8/5 11/8/4/1 9/4/7/1 0.75
interstitial fibrosis and tubular atrophy (score) 1.00(1.00) 1.00(1.00) 1.00(1.00) 0.77
0.85 ± 0.87 0.67 ± 0.48 0.62 ± 0,50  
Vascular sclerosis (score) 1.00(2.00) 1.00 (2.00) 0.00(2.00) 0.68
0.91 ± 0,95 1.00 ± 1, 02 0.76 ± 1.14  
Immunohistological staining
IgG (score) 2.00(1.50) 2.00(0.75) 2.00(2.00) 0.86
1.49 ± 0.87 1.63 ± 0.71 1.43 ± 0.93  
IgG1 (score) 0.00(0.00) 0.00(1.00) 0.00(1.00) 0.41
0.21 ± 0.55 0.33 ± 0.57 0.38 ± 0.67  
IgG4 (score) 0.00(0.00) 0.00(1.00) 0.00(1.00) 0.43
0.24 ± 0.61 .0.38 ± 0.65 0.43 ± 0.75  
C3 (score) 1.00(1.00) 1.00(1.00) 0.00(1.00) 0.09
0.73 ± 0.76 0.71 ± 0.46 0.38 ± 0.59  
C4 (score) 0.00(0.00) 0.00(0.00) 0.00(0.00) 0.83
0.13 ± 0.42 0.08 ± 0.28 0.48 ± 0.22  
C1q (score) 0.00(0.00) 0.00(0.00) 0.00(0.00) 0.31
0.09 ± 0.30 0.13 ± 0.45 0.19 ± 0.51  
Fib (score) 0.00(0.00) 0.00(0.00) 0.00(0.00) 0.86
0.06 ± 0.24 0.08 ± 0.28 0.05 ± 0.22  
lgM (score) 0.00(0.00) 0.00(0.00) 0.00(0.00) 0.32
0.03 ± 0.17 0.08 ± 0.36 0.14 ± 0.36  
IgA (score) 0.00(0.00) 0.00(0.00) 0.00(0.00) 0.99
0.12 ± 0.42 0.08 ± 0.26 0.10 ± 0.30