Skip to main content

Table 2 pHi recovery rate in control and treated podocytes

From: Angiotensin II-induced podocyte apoptosis is mediated by endoplasmic reticulum stress/PKC-δ/p38 MAPK pathway activation and trough increased Na+/H+ exchanger isoform 1 activity

  dpHi/dt (Units/min)   n
NMDG, 138 mM 0.045 ± 0.006   11
Control solution, Na+ 138 mM, added after NMDG solution 0.179 ± 0.025a   11
Control solution, Na+ 138 mM 0.176 ± 0.016   10
AII 1 μM 0.372 ± 0.028c   10
Losartan (1 μM) 0.220 ± 0.017   11
AII/Losartan (1 μM) 0.217 ± 0.029d   8
Cariporide (10 μM) 0.061 ± 0.006b   6
AII/Cariporide (10 μM) 0.067 ± 0.005 db   10
SB203580 (0.1 μM) 0.177 ± 0.023   6
AII/ SB203580 (0.1 μM) 0.217 ± 0.036e   7
  1. Values are mean ± SEM. n, number of experiments. ap < 0.001 versus NMDG (N-methyl-D-glucamine); bp < 0.001 versus control; cp < 0.001 versus control; dp < 0.001 versus angiotensin II (AII) and e p < 0.01 versus AII