Table 2 Univariate analysis of predictors of AKI
From: Preoperative serum uric acid predicts incident acute kidney injury following cardiac surgery
Variables | Odds ratio (CI 95%) | P-value |
|---|---|---|
Serum uric acid > median | 4680 (1.840; 11.904) | 0.001 |
Demographics | ||
Age > 60 yr | 1.749 0.581; 5.263 | 0.467 |
Male gender | 0.840 (0.379; 1.860) | 0.682 |
BMI > 30 kg/m2 | 3.220 (1.472; 7.045) | 0.004 |
Surgery type: n (%) | ||
Valves | 1.782 (0.827; 3.839) | 0.161 |
Bypass | 0.418 (0.178; 0.979) | 0.049 |
Valves + Bypass | 1.481 (0.592; 3.704) | 0.444 |
Renal function | ||
Serum- Creatinine > median | 4.509 (1.967; 10.338) | < 0.001 |
CKD- Epi- GFR < 60 ml/min | 2.875 (1.321; 6.257) | 0.009 |
Comorbidities: n (%) | ||
Hypertension | 1.357 (0.300; 6.143) | 1.000 |
CKD | 3.938 (1.763; 8.800) | 0.001 |
Diabetes | 2.609 (1.195; 5.695) | 0.017 |
PVD | 1.990 (0.739; 5.355) | 0.228 |
Congestive heart failure | 1.553 (0.563; 4.284) | 0.488 |
COPD | 1.896 (0.706; 5.091) | 0.237 |
Previous heart surgery | 3.280 (1.238; 8.689) | 0.021 |
Medication: n (%) | ||
ACE- Inhibitor | 1.131 (0.503; 2.544) | 0.839 |
AT1- Receptor- Blocker | 1.289 (0.452; 3.671) | 0.579 |
Calcium Antagonist | 2.206 (0.962; 5.056) | 0.064 |
Βeta- Blocker | 1.260 (0.526; 3.014) | 0.672 |
Diuretic | 1.783 (0.801; 3.971) | 0.161 |
Lipid- lowering drugs | 0.688 (0.307; 1.546) | 0.421 |
Allopurinol | 0.476 (0.060; 3.769) | 0.700 |
Intraoperative parameters | ||
Operation time > 300 min | 4.466 (1.795; 11.115) | 0.002 |
CPB- time > 90 min | 4.360 (1.854; 10.252) | 0.001 |
ACC- time > median | 2.502 (1.124; 5.572) | 0.036 |
PRBC transfusion | 0.710 (0.327; 1.540) | 0.420 |
FFP transfusion | 2.776 (1.279; 6.024) | 0.012 |
Need for reoperation | 5.132 (2.164; 12.170) | < 0.001 |