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Table 2 Univariate analysis of predictors of AKI

From: Preoperative serum uric acid predicts incident acute kidney injury following cardiac surgery

Variables Odds ratio (CI 95%) P-value
Serum uric acid > median 4680 (1.840; 11.904) 0.001
Demographics
 Age > 60 yr 1.749 0.581; 5.263 0.467
 Male gender 0.840 (0.379; 1.860) 0.682
 BMI > 30 kg/m2 3.220 (1.472; 7.045) 0.004
Surgery type: n (%)
 Valves 1.782 (0.827; 3.839) 0.161
 Bypass 0.418 (0.178; 0.979) 0.049
 Valves + Bypass 1.481 (0.592; 3.704) 0.444
Renal function
 Serum- Creatinine > median 4.509 (1.967; 10.338) < 0.001
 CKD- Epi- GFR < 60 ml/min 2.875 (1.321; 6.257) 0.009
Comorbidities: n (%)
 Hypertension 1.357 (0.300; 6.143) 1.000
 CKD 3.938 (1.763; 8.800) 0.001
 Diabetes 2.609 (1.195; 5.695) 0.017
 PVD 1.990 (0.739; 5.355) 0.228
 Congestive heart failure 1.553 (0.563; 4.284) 0.488
 COPD 1.896 (0.706; 5.091) 0.237
 Previous heart surgery 3.280 (1.238; 8.689) 0.021
Medication: n (%)
 ACE- Inhibitor 1.131 (0.503; 2.544) 0.839
 AT1- Receptor- Blocker 1.289 (0.452; 3.671) 0.579
 Calcium Antagonist 2.206 (0.962; 5.056) 0.064
 Βeta- Blocker 1.260 (0.526; 3.014) 0.672
 Diuretic 1.783 (0.801; 3.971) 0.161
 Lipid- lowering drugs 0.688 (0.307; 1.546) 0.421
 Allopurinol 0.476 (0.060; 3.769) 0.700
Intraoperative parameters
 Operation time > 300 min 4.466 (1.795; 11.115) 0.002
 CPB- time > 90 min 4.360 (1.854; 10.252) 0.001
 ACC- time > median 2.502 (1.124; 5.572) 0.036
 PRBC transfusion 0.710 (0.327; 1.540) 0.420
 FFP transfusion 2.776 (1.279; 6.024) 0.012
 Need for reoperation 5.132 (2.164; 12.170) < 0.001
  1. BMI Body mass index, CKD- Epi- GFR Chronic Kidney Disease Epidemiology Collaboration Glomerular Filtration Rate, CKD Chronic Kidney Disease, PVD Peripheral Vascular Disease, COPD Chronic Obstructive Pulmonary Disease, ACE Angiotensin- converting Enzyme; AT1- Receptor- Blocker Angiotensin- 1- Receptor- Blocker, CPB Cardiopulmonary Bypass, ACC Aortic Cross Clamp, PRBC Packed Red Blood Cells, FFP Fresh Frozen Plasma