|Reference||Main Results||Timing of serology taken||Main conclusions||Study quality|
|Renal transplant patients/recipients||Haemodialysis patients||Renal transplant candidates +|
|Crespo JF, et al. (2002) ||Among 336 renal transplant candidates, 33 (9.8%) were seronegative.||Before contraction of primary varicella||–||Level 2|
|Geel AL, et al. (2006) ||
Among 854 transplant recipients,|
2.1% were seronegative.
|Among 286 patients on the wait list, 3.2% patients were seronegative||Before contraction of primary varicella||
-Low prevalence of seronegativity.|
-At risk of severe complications after contact with chickenpox.
|Rodríguez-Moreno A, et al. (2006) ||Among the four patients that developed primary varicella infection, all were tested negative for VZV IgG.||Presentation/onset of primary varicella||-Varicella infection among renal allograft recipients is unusual but carries a high morbidity and mortality.||Level 3|
|Kaul A, et al. (2012) ||Among 23 renal allograft patients that developed varicella infection, all was tested negative for VZV IgG.||Presentation/onset of primary varicella||–||Level 3|
|Talebi-Taher M, et al. (2013) ||Among 187 patients on haemodialysis, 2.1% were seronegative.||Before contraction of primary varicella||
-No correlation between patient’s self-reported history of VZV infection and seroprevalence status (p = 0.6).|
-Serologic screening for VZV for transplant candidates is essential.
-Consider this population as a target group for future national immunisation program.
|Abad CL, et al. (2016) ||
Among 54 cases of varicella in transplant recipients, baseline serology available in 32 patients,|
19 (59.4%) were seronegative.
|Presentation/onset of primary varicella||
Baseline serologies before transplantation remains useful as markers for prior exposure and latent infection.|
It also guides VZV vaccination.
|Ong CY, et al. (2018) ||Among 66 cases of varicella in patients with ESRD (dialysis, transplant, conservative), baseline serology available in 19 patients. 42.1% were seronegative.||Presentation/onset of primary varicella||
-Immunity to varicella should be screened among ESRD patients.|
-Seronegative patients to be considered for varicella vaccination.