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Fig. 1 | BMC Nephrology

Fig. 1

From: NGAL protects against endotoxin-induced renal tubular cell damage by suppressing apoptosis

Fig. 1

a SCr in rats subjected to LPS at 6 h. The data show SCr of Con and sAKI, with means ± SD values/group obtained by colorimetric assay (μM/L). SCr increased in rats with sAKI. SCr: serum creatinine, LPS: lipopolysaccharide. **p < 0.01, relative to the Con group. b Renal histological injury observed under light microscopy at 6 h after LPS treatment (H&E, 200×). Histopathlogical changes included renal tubular epithelial swelling and inflammatory cell infiltration without glomerular injury. c uNGAL in rats subjected to LPS at 6 h. Data show respective uNGAL of Con and sAKI, with means ± SD values/group obtained by ELISA (ng/mL). uNGAL was significantly increased in rats with sAKI. uNGAL: urine NGAL, LPS: lipopolysaccharide. ***p < 0.001, relative to the con group

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