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Table 1 Laboratory findings of the proband during the hospitalization and 3-year follow-up

From: Familial hypomagnesaemia, Hypercalciuria and Nephrocalcinosis associated with a novel mutation of the highly conserved leucine residue 116 of Claudin 16 in a Chinese patient with a delayed diagnosis: a case report

Items

First Admission

First follow-up

Second follow-up

Third follow-up

Fourth follow-up

Normal Range

Date

Mar, 2013

Mar, 2014

Aug, 2014

Feb, 2016

Jun, 2016

 

Age (yrs)

33

34

34

36

36

 

SCr (μmol/L)

250

270

306

537

647

31–132

eGFRa (ml/min/1.73m2)

21.1

19.1

16.4

8.2

6.5

> 90

SK (mmol/L)

4.2

4.3

4.4

4.9

4.7

3.5–5.5

SMg (mmol/L)

0.65

NA

0.70

0.99

0.91

0.65–1.20

SCa (mmol/L)

1.42

1.63

1.68

1.81

1.58

2.11–2.52

SP (mmol/L)

1.7

2.0

1.5

2.0

2.1

0.8–1.6

HCO3 (mmol/L)

22.0

21.0

20.0

23.7

21.7

23.0–31.0

ALB (g/L)

37.2

NA

47.8

39.6

46.5

35.0–55.0

ALP (U/L)

40.8

NA

NA

NA

60.9

35–125

PTH (pg/ml)

65.6

74.5

75.6

73.8

94.5

15.0–65.0

UpH

5.0

5.0

NA

NA

NA

 

24 h-UCa (mmol/1.73m2)

3.9

4.3

3.8

2.1

2.0

2.5–5.5

UCa/Cr (mol/mol)

NA

0.61

0.57

0.46

0.44

0.15–0.33

24 h-UMg (mmol/1.73m2)

NA

7.1

7.0

3.9

4.2

 

FEMgb

NA

38.5%

43.7%

35.9%

52.7%

< 5.0%

25OH-VitD

NA

NA

NA

NA

22.4

20.0—32.0

UProtein

1.07 g/24 h

+

NA

NA

+

Negative

  1. eGFR Estimated glomerular filtration rate, S Serum, ALB Albumin, ALP Alkaline phosphate, PTH Parathyroid hormone, U Urine, NA Not available. a, Calculated by CKD-EPI formula; b, Calculated by the following formula: UMg × SCr/(0.7 × SMg × UCr) × 100%