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Fig. 7 | BMC Nephrology

Fig. 7

From: Efficacy of Hydroxy-L-proline (HYP) analogs in the treatment of primary hyperoxaluria in Drosophila Melanogaster

Fig. 7

Showing fluorescence microscope images of standard growth medium for the three inhibitors with increasing low, moderate and high concentrations respectively. a, e and i were controls at 0% Baclofen, N-Acetyl-L-Hydroxyproline (N-THOP) Vitamin B6 respectively with high numbers of CaOx crystals, b Baclofen, 0.01% showed litile inhibition effects and a great deal of CaOx crystals still visible, c 0.05% Baclofen, showing slight reduction in the amount of crystals, d 0.1% Baclofen with much improved reduction in the amount of CaOx crystals, f 0.05% N-Acetyl-L-Hydroxyproline (N-THOP) less or no reduction in the inhibition of CaOx, g 0.2% N-Acetyl-L-Hydroxyproline (N-THOP), greatly inhibited the amount of CaOx crystals, h 1% N-Acetyl-L-Hydroxyproline (N-THOP) showing significantly reduced amount of CaOx crystals to almost a single crystal, j 0.5% Vitamin B6 still with a high amount CaOx crystals, k 2% Vitamin B6 showing moderate amount CaOx crystals, l 3% Vitamin B6 showing hardly any CaOx crystals

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