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Table 1 Baseline characteristics of subjects by uric acid quartiles (Q1-Q4) at baseline (male)

From: The association between time-mean serum uric acid levels and the incidence of chronic kidney disease in the general population: a retrospective study

Serum uric acid(mg/dl) Male Q1
(≤5.5)
Q2
(> 5.5, ≤6.2)
Q3
(> 6.2, ≤6.9)
Q4
(> 6.9)
P value*
N 3176 817 794 718 847  
Age (years) 48 (24) 48 (26) 44 (22) 47 (23) 50 (23) 0.001
BMI (kg/m2) 24.0±2.9 22.8±2.8 23.7±2.7 24.3±2.8 25.0±2.9 < 0.001
Overweight (24 ≤ BMI < 28) (%) 1329 (41.8) 233 (28.5) 311 (39.2) 332 (46.2) 453 (53.5) < 0.001
Obesity (BMI ≥ 28) (%) 249 (7.8) 33 (4.0) 41 (5.2) 67 (9.3) 108 (12.8) < 0.001
Systolic BP (mmHg) 128.6±17.4 126.9±17.7 127.2±17.2 129.3±17.5 130.9±16.8 < 0.001
Diastolic BP (mmHg) 78.0±10.8 76.2±10.8 77.2±11.1 78.6±10.4 79.9±10.7 < 0.001
Total cholesterol (mmol/L) 4.8±0.9 4.7±0.9 4.7±0.9 4.8±0.9 5.0±0.9 < 0.001
Triglycerides (mmol/L) 1.6±1.3 1.3±1.2 1.4±1.0 1.6±1.0 2.0±1.7 < 0.001
HDL cholesterol (mmol/L) 1.2±0.3 1.3±0.3 1.2±0.2 1.2±0.2 1.1±0.2 < 0.001
LDL cholesterol (mmol/L) 2.8±0.7 2.7±0.7 2.8±0.7 2.9±0.8 2.9±0.8 < 0.001
BUN (mmol/L) 5.2±1.1 5.1±1.2 5.2±1.1 5.3±1.1 5.3±1.1 0.031
Fasting plasma glucose (mmol/L) 5.3±0.9 5.3±1.1 5.2±0.8 5.3±0.9 5.3±0.8 0.019
eGFR (ml/min/1.73m2) 84.9±13.7 88.2±13.7 86.2±13.7 84.9±13.9 80.6±12.3 < 0.001
Serum uric acid (mg/dl) 6.3±1.2 4.9±0.5 5.9±0.2 6.5±0.2 7.7±0.7 < 0.001
Hypertension (%) 560 (17.6) 125 (15.3) 114 (14.4) 137 (19.1) 184 (21.7) < 0.001
Diabetes (%) 136 (4.3) 43 (5.3) 30 (3.8) 27 (3.8) 36 (4.3) 0.409
New incident CKD (%) 139 (4.4) 22 (2.7) 22 (2.8) 31 (4.3) 64 (7.6) < 0.001
  1. *P value by ANOVA for continuous variables and chi square test for categorical variables
  2. BMI body mass index, eGFR estimated glomerular filtration rate, BUN blood urea nitrogen, HDL high-density lipoprotein, LDL low-density lipoprotein, eGFR estimated glomerular filtration rate, CKD chronic kidney disease. Data were expressed as mean ± SD, median (interquartile range), or percentage (%)