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Table 2 Baseline characteristics of subjects by uric acid quartiles (Q1-Q4) at baseline (female)

From: The association between time-mean serum uric acid levels and the incidence of chronic kidney disease in the general population: a retrospective study

Serum uric acid(mg/dl) Female Q1
(≤4.0)
Q2
(> 4.0, ≤4.5)
Q3
(> 4.5, ≤5.2)
Q4
(> 5.2)
P value*
N 2007 548 440 524 495  
Age (years) 49 (22) 45 (18) 46 (19) 48 (23) 58 (25) < 0.001
BMI (kg/m2) 22.1±2.8 21.1±2.6 21.7±2.5 22.1±2.7 23.5±3.1 < 0.001
Overweight (24 ≤ BMI < 28) (%) 402 (20.0) 73 (13.3) 62 (14.1) 99 (18.9) 168 (33.9) < 0.001
Obesity (BMI ≥ 28) (%) 62 (3.1) 5 (0.9) 6 (1.4) 16 (3.1) 35 (7.1) < 0.001
Systolic BP (mmHg) 120.6±19.1 116.4±17.2 118.3±16.9 120.1±19.3 128.0±20.9 < 0.001
Diastolic BP (mmHg) 71.7±11.0 69.8±10.2 70.9±10.6 71.5±10.7 74.7±11.8 < 0.001
Total cholesterol (mmol/L) 4.9±0.9 4.7±0.9 4.8±0.9 4.9±0.9 5.2±1.0 < 0.001
Triglycerides (mmol/L) 1.2±0.8 1.0±0.6 1.0±0.5 1.2±0.9 1.5±1.0 < 0.001
HDL cholesterol (mmol/L) 1.5±0.3 1.5±0.3 1.5±0.3 1.4±0.3 1.4 ±0.3 < 0.001
LDL cholesterol (mmol/L) 2.8±0.8 2.6±0.7 2.7±0.7 2.8±0.8 3.0±0.8 < 0.001
BUN (mmol/L) 4.7±1.1 4.5±1.1 4.6±1.1 4.6±1.1 5.0±1.1 < 0.001
Fasting plasma glucose (mmol/L) 5.1±0.7 5.0±0.6 5.1±0.6 5.1±0.6 5.3±0.8 < 0.001
eGFR (ml/min/1.73m2) 88.3±17.4 92.7±17.8 89.4±17.7 88.3±17.1 82.4±15.2 < 0.001
Serum uric acid (mg/dl) 4.7±1.0 3.5±0.4 4.3±0.1 4.8±0.2 5.9±0.6 < 0.001
Hypertension (%) 288 (14.3) 39 (7.1) 49 (11.1) 75 (14.3) 126 (25.5) < 0.001
Diabetes (%) 61 (3.0) 5 (0.9) 14 (3.2) 16 (3.1) 27 (5.5) < 0.001
New incident CKD (%) 88 (4.4%) 9 (1.6%) 11 (2.5%) 21 (4.0%) 47 (9.5%) < 0.001
  1. *P value by ANOVA for continuous variables and chi square test for categorical variables
  2. BMI body mass index, eGFR estimated glomerular filtration rate, BUN blood urea nitrogen, HDL high-density lipoprotein, LDL low-density lipoprotein, eGFR estimated glomerular filtration rate, CKD chronic kidney disease. Data were expressed as mean ± SD, median (interquartile range), or percentage (%)