Table 3 Baseline characteristics of participants relative to development of CKD during the 6-year follow-up period
CKD | Without CKD | P value* | |
|---|---|---|---|
N | 227 | 4956 | |
Male (%) | 139 (61.2) | 3037 (61.3) | 0.989 |
Age (years) | 72 (23) | 47 (22) | < 0.001 |
BMI (kg/m2) | 24.3±2.8 | 23.2±3.0 | < 0.001 |
Overweight (24 ≤ BMI < 28) (%) | 110 (48.5) | 1621 (32.7) | < 0.001 |
Obesity (BMI ≥ 28) (%) | 22 (9.7) | 289 (5.8) | 0.017 |
Systolic BP (mmHg) | 139.8±20.8 | 124.9±18.1 | < 0.001 |
Diastolic BP (mmHg) | 80.6±12.0 | 75.3±11.2 | < 0.001 |
Total cholesterol (mmol/L) | 5.1±1.0 | 4.8±0.9 | < 0.001 |
Triglycerides (mmol/L) | 1.7±1.3 | 1.4±1.1 | 0.001 |
HDL cholesterol (mmol/L) | 1.3±0.3 | 1.3±0.3 | 0.048 |
LDL cholesterol (mmol/L) | 3.0±0.8 | 2.8±0.8 | < 0.001 |
BUN (mmol/L) | 5.7±1.2 | 5.0±1.1 | < 0.001 |
Fasting plasma glucose (mmol/L) | 5.5±1.0 | 5.2±0.8 | < 0.001 |
eGFR (ml/min/1.73m2) | 68.7±7.6 | 87.0±15.1 | < 0.001 |
Serum uric acid (mg/dl) | 6.24±1.41 | 5.59±1.33 | < 0.001 |
Time-mean serum uric acid (mg/dl) | 6.39±1.29 | 5.64±1.28 | < 0.001 |
Hyperuricemia (%) | 81 (35.7) | 836 (16.9) | < 0.001 |
Hypertension (%) | 103 (45.4) | 746 (15.1) | < 0.001 |
Diabetes (%) | 25 (11.0) | 173 (3.5) | < 0.001 |