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Table 3 Baseline characteristics of participants relative to development of CKD during the 6-year follow-up period

From: The association between time-mean serum uric acid levels and the incidence of chronic kidney disease in the general population: a retrospective study

  CKD Without CKD P value*
N 227 4956  
Male (%) 139 (61.2) 3037 (61.3) 0.989
Age (years) 72 (23) 47 (22) < 0.001
BMI (kg/m2) 24.3±2.8 23.2±3.0 < 0.001
Overweight (24 ≤ BMI < 28) (%) 110 (48.5) 1621 (32.7) < 0.001
Obesity (BMI ≥ 28) (%) 22 (9.7) 289 (5.8) 0.017
Systolic BP (mmHg) 139.8±20.8 124.9±18.1 < 0.001
Diastolic BP (mmHg) 80.6±12.0 75.3±11.2 < 0.001
Total cholesterol (mmol/L) 5.1±1.0 4.8±0.9 < 0.001
Triglycerides (mmol/L) 1.7±1.3 1.4±1.1 0.001
HDL cholesterol (mmol/L) 1.3±0.3 1.3±0.3 0.048
LDL cholesterol (mmol/L) 3.0±0.8 2.8±0.8 < 0.001
BUN (mmol/L) 5.7±1.2 5.0±1.1 < 0.001
Fasting plasma glucose (mmol/L) 5.5±1.0 5.2±0.8 < 0.001
eGFR (ml/min/1.73m2) 68.7±7.6 87.0±15.1 < 0.001
Serum uric acid (mg/dl) 6.24±1.41 5.59±1.33 < 0.001
Time-mean serum uric acid (mg/dl) 6.39±1.29 5.64±1.28 < 0.001
Hyperuricemia (%) 81 (35.7) 836 (16.9) < 0.001
Hypertension (%) 103 (45.4) 746 (15.1) < 0.001
Diabetes (%) 25 (11.0) 173 (3.5) < 0.001
  1. *P value by T-test for continuous variables and chi-square test for categorical variables. BMI body mass index, eGFR estimated glomerular filtration rate, BUN blood urea nitrogen, HDL high-density lipoprotein, LDL low-density lipoprotein, eGFR estimated glomerular filtration rate, CKD chronic kidney disease. Data were expressed as mean ± SD, median (interquartile range), or percentage (%)