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Table 1 Clinical and Epidemiological characteristics of living and deceased donors

From: Molecular profile of urine extracellular vesicles from normo-functional kidneys reveal minimal differences between living and deceased donors

 

uEV Analysis

Age

Gender

HTA

DM2

DLP

Others

SrCr (mg/dL)

Remuzzi Score

Cause of death

Drugs

ICU Drugs

RK

LK

LD1

P,T

40–45

F

0.7

LD2

P,T

55–60

F

0.98

LD3

P,T

65–70

M

0.63

LD4

P,T

50–55

M

Yes

Hipotirodism

0.93

simvastatin, Levotiroxine

LD5

P,T

55–60

F

1.02

DD1

P, T

65–70

F

Yes

Yes

0.8

3

3

CVA

Olmesartan, Lormetazepam

noradrenaline, furosemide

DD2

P, T

65–70

F

Yes

obesity

0.8

5

5

Ictus

metformine, insuline

clopidogrelt, amoxiciline-clavulanic

DD3

P,T

80–85

F

Yes

Yes

1.5

4

5

CVA

bisoprolol,torasemide, lorazepam, sertralin, simvastatin

DD4

T

75–80

M

Yes

Yes

Yes

1.8

4

4

Trauma

Triflusal;enalapril; Metformin; Gliclazide; Ezetimibe; Allopurinol; Glucosamine; Tenoxicam; Omeprazole

manitol, actocortine, noradrenaline,

DD5

T

55–60

M

Yes

1.56

2

Cardiac event

Losartan, Atorvastatin, fenofibrate

propofol, atropine, midazolam, noradrenaline

DD6

P

45–50

M

Bone cyst

3.41

2

2

PTE

oxcarbazepine, diazepam, Celecoxib.

adrenaline

DD7

P

70–75

F

Yes

osteoporosis

0.73

3

2

Ictus

Calcium

noradrenaline

  1. A summary of the age, gender, diseases, cause of death and medication of all the patients is included in this Table. P: sample used for proteomic assays. T: sample used for NGS assays
  2. F female, M male; HTA Hypertension, DM2 Diabetes Mellitus type 2, DLP Dyslipemia, CVA cerebrovascular accident, PTE Pulmonary thrombo-embolism, SrCr Serum Creatinine, RK right kidney, LK left kidney