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Table 2 Demographics of the study population at baseline

From: Effect of haemodiafiltration vs conventional haemodialysis on growth and cardiovascular outcomes in children – the HDF, heart and height (3H) study

  Haemodialysis n (%) or Median (IQR) Haemodiafiltration n (%) or Median (IQR) p
Number 106 71  
Age
 5–10 22 (20.8) 15 (21) 0.78
 10–15 37 (34.9) 27 (38)
 15–20 47 (44.3) 29 (41)
Gender (female) 45 (42) 43 (60) 0.03
Ethnicity
 Caucasian / Asian / African /other 66 / 21 / 9 /’10 46 / 17 / 5 / 3 0.42
Underlying renal diagnosis
 Dysplasia 54 (51) 32 (45) 0.76
 Glomerulonephritis 25 (24) 19 (26)
 Cystic kidney disease 4 (4) 5 (7)
 Other 17 (15) 11 (16)
 Unknown 6 (6) 4 (6)
Presence of comorbidities 0.81
 Impaired cognitive development 22 (21) 14 (20)
 Impaired motor development 11 (10) 6 (8)
 Ocular or hearing abnormalities 18 (17) 11 (15)
 Other abnormalities 25 (24) 13 (18)
 Confirmed genetic disorder 17 (16) 12 (17)
Previous dialysis 35 (33) 34 (48) 0.07
 Modality (PD / HD / both) 22 / 8 / 5 14 / 14 / 6 0.17
 Cumulative time on dialysis before study (months) 24 (10, 52) 28 (16, 45) 0.92
Previous transplant 18 (17) 21 (29) 0.06
 Time with functioning graft (mts) 33 (16, 96) 66 (12, 114) 0.96
Residual urine volume (ml/day)
  < 200 / 200–500 / > 500 66 (62) / 22 (21) / 18 (17) 44 (62) / 13 (18) / 14(20) 0.85
Details of dialysis therapy
Filter
 High flux / Mid flux / Low flux 67 (63) / 24 (23) / 15(14) 71 (100) < 0.00001
Dialysis water qualitya
 Pure vs ultrapure 51 (48) / 55 (52) 71 (100) < 0.00001
Vascular accessb
 AVF / CVL / AVG 34 (33) / 71 (67) / 1 (1) 27 (38) / 42 (59) / 2(3) 0.34
Blood flow /m2 body surface area 182 (148, 215) 174 (144, 205) 0.40
Dialysate sodium
  ≤ 138 mmol/l 76 (72) 49 (69) 0.79
  > 138 mmol/l 30 (28) 22 (31)
Dialysate bicarbonate
 32–35 mMol/L 68 (64) 42 (59) 0.48
 36–42 mMol/L 38 (36) 29 (41)
  1. IQR – interquartile range; aDialysate water quality: Pure dialysis fluid is defined as containing < 100 colony-forming unit/ml (CFU/ml) and < 0.25 endotoxin unit/ml (EU/ml). Ultrapure dialysis fluid is defined as containing < 0.1 CFU/ml and < 0.03 EU/ml; bVascular access: AVF – arteriovenous fistula; CVL – central venous line; AVG – arteriovenous graft